Blocking the Self‐Destruct Program of Dopamine Neurons through Macrophage Migration Inhibitory Factor Nuclease Inhibition
Parkinson's disease (PD) is a progressive neurodegenerative condition that
pathognomonically involves the death of dopaminergic neurons in the substantia nigra pars …
pathognomonically involves the death of dopaminergic neurons in the substantia nigra pars …
Allosteric inhibitors of macrophage migration inhibitory factor (MIF) Interfere with Apoptosis-Inducing factor (AIF) Co-Localization to prevent Parthanatos
Macrophage migration inhibitory factor (MIF) is a multifunctional cytokine and essential
signaling protein associated with inflammation and cancers. One of the newly described …
signaling protein associated with inflammation and cancers. One of the newly described …
2, 5-Pyridinedicarboxylic acid is a bioactive and highly selective inhibitor of D-dopachrome tautomerase
Macrophage migration inhibitory factor (MIF) and D-dopachrome tautomerase (D-DT) are
two pleotropic cytokines, which are coexpressed in various cell types to activate the cell …
two pleotropic cytokines, which are coexpressed in various cell types to activate the cell …
The C-terminal Region of D-DT Regulates Molecular Recognition for Protein–Ligand Complexes
Systematic analysis of molecular recognition is critical for understanding the biological
function of macromolecules. For the immunomodulatory protein D-dopachrome tautomerase …
function of macromolecules. For the immunomodulatory protein D-dopachrome tautomerase …
Design and synthesis of ligands targeting MIF family enzymes and their application in medicinal chemistry
A Osipyan - 2023 - research.rug.nl
University of Groningen Design and synthesis of ligands targeting MIF family enzymes and
their application in medicinal chemistr Page 1 University of Groningen Design and synthesis …
their application in medicinal chemistr Page 1 University of Groningen Design and synthesis …
Structural and Functional Studies of the Human Members of the Macrophage Migration Inhibitory Factor Family
A Parkins - 2024 - search.proquest.com
Macrophage migration inhibitory factor (MIF) and D-dopachrome tautomerase (D-DT) are
the two human members of the MIF superfamily, which are implicated in an array of …
the two human members of the MIF superfamily, which are implicated in an array of …
Emerging opportunities to target gene transcription and DNA repair in drug discovery
D Chen - 2023 - research.rug.nl
After the completion of the Human Genome Project, biological research in the post-genomic
era has focused on interpreting the biological functions of genes and their products. This …
era has focused on interpreting the biological functions of genes and their products. This …