Antimicrobial resistance is a growing threat to global public health that calls for innovative strategies to develop new methods of action against resistance to emerging infectious …
With the widespread rise of antimicrobial resistance, most traditional sources for new drug compounds have been explored intensively for new classes of antibiotics. Meanwhile, metal …
S Zoffmann, M Vercruysse, F Benmansour, A Maunz… - Scientific reports, 2019 - nature.com
Identification of novel antibiotics remains a major challenge for drug discovery. The present study explores use of phenotypic readouts beyond classical antibacterial growth inhibition …
Abstract FTIR, NMR, CHN and single crystal X-ray crystallography were used to validate a series of three new triorganotin (IV) carboxylate complexes, R 3 Sn (L) for R= Methyl (1), n …
We are facing a potential catastrophe of untreatable bacterial infections, driven by the inexorable rise of extensively drug-resistant bacteria, coupled with a market failure of …
A series of three isomeric 4-[(n-bromophenyl) carbamoyl] butanoic acids (n= 2, 3 and 4) were synthesized and their structures were confirmed by FTIR, NMR, MS, micro elemental …
EE Vinogradova, AL Alekseenko, SV Popkov… - International Journal of …, 2023 - mdpi.com
A series of S-alkyl substituted thioglycolurils was prepared through the alkylation of corresponding thioglycolurils with halogenoalkanes and tested for their fungicidal activity …
Three triorganotin (IV) compounds, R3Sn (L), with R= CH3 (1), n-C4H9 (2) and C6H5 (3), and LH= 4-[(2-chloro-4-methylphenyl) carbamoyl] butanoic acid, were prepared and …
O Zalevskaya, Y Gur'eva, A Kutchin, KA Hansford - Antibiotics, 2020 - mdpi.com
In an era of multidrug-resistant bacterial infections overshadowed by a lack of innovation in the antimicrobial drug development pipeline, there has been a resurgence in …