HPV16 and HPV18 genome structure, expression, and post-transcriptional regulation

L Yu, V Majerciak, ZM Zheng - International journal of molecular sciences, 2022 - mdpi.com
Human papillomaviruses (HPV) are a group of small non-enveloped DNA viruses whose
infection causes benign tumors or cancers. HPV16 and HPV18, the two most common high …

Epigenetic regulation of human papillomavirus transcription in the productive virus life cycle

M Burley, S Roberts, JL Parish - Seminars in immunopathology, 2020 - Springer
Human papillomaviruses (HPV) are a large family of viruses which contain a circular, double-
stranded DNA genome of approximately 8000 base pairs. The viral DNA is chromatinized by …

Epigenetics and genetics of viral latency

PM Lieberman - Cell host & microbe, 2016 - cell.com
Viral latency can be considered a metastable, nonproductive infection state that is capable
of subsequent reactivation to repeat the infection cycle. Viral latent infections have …

[HTML][HTML] Control of human papillomavirus gene expression by alternative splicing

SV Graham, AAA Faizo - Virus research, 2017 - Elsevier
Human papillomaviruses possess circular double stranded DNA genomes of around 8 kb in
size from which multiple mRNAs are synthesized during an infectious life cycle. Although at …

Viral remodeling of the 4D nucleome

KD Kim, PM Lieberman - Experimental & Molecular Medicine, 2024 - nature.com
The dynamic spatial organization of genomes across time, referred to as the four-
dimensional nucleome (4DN), is a key component of gene regulation and biological fate …

Epigenetic regulation of the human papillomavirus life cycle

M Mac, CA Moody - Pathogens, 2020 - mdpi.com
Persistent infection with certain types of human papillomaviruses (HPVs), termed high risk,
presents a public health burden due to their association with multiple human cancers …

Keratinocyte differentiation-dependent human papillomavirus gene regulation

SV Graham - Viruses, 2017 - mdpi.com
Human papillomaviruses (HPVs) cause diseases ranging from benign warts to invasive
cancers. HPVs infect epithelial cells and their replication cycle is tightly linked with the …

Mechanisms by which HPV induces a replication competent environment in differentiating keratinocytes

CA Moody - Viruses, 2017 - mdpi.com
Human papillomaviruses (HPV) are the causative agents of cervical cancer and are also
associated with other genital malignancies, as well as an increasing number of head and …

STAT3 activation by E6 is essential for the differentiation-dependent HPV18 life cycle

EL Morgan, CW Wasson, L Hanson, D Kealy… - PLoS …, 2018 - journals.plos.org
Human papillomaviruses (HPV) activate a number of host factors to control their
differentiation-dependent life cycles. The transcription factor signal transducer and activator …

The role of E6 spliced isoforms (E6*) in human papillomavirus-induced carcinogenesis

L Olmedo-Nieva, JO Muñoz-Bello… - Viruses, 2018 - mdpi.com
Persistent infections with High Risk Human Papillomaviruses (HR-HPVs) are the main
cause of cervical cancer development. The E6 and E7 oncoproteins of HR-HPVs are derived …