[HTML][HTML] Acute Myeloid Leukemia in Older Patients: From New Biological Insights to Targeted Therapies
P Niscola, V Gianfelici, G Catalano… - Current …, 2024 - pmc.ncbi.nlm.nih.gov
Acute myeloid leukemia (AML) is a heterogeneous blood-related neoplasm that
predominantly afflicts older adults with a poor prognosis due to their physical condition and …
predominantly afflicts older adults with a poor prognosis due to their physical condition and …
[HTML][HTML] Membrane Antigen Targeting in Acute Myeloid Leukemia Using Antibodies or CAR-T Cells
U Testa, G Castelli, E Pelosi - Cancers, 2024 - mdpi.com
This review explores the emerging area of the therapeutic use of antibodies and chimeric
antigen receptor (CAR)-T cells for the treatment of acute myeloid leukemia (AML). Through a …
antigen receptor (CAR)-T cells for the treatment of acute myeloid leukemia (AML). Through a …
A scalable computational framework for annotation-independent combinatorial target identification in scRNA-seq databases
The applicability of novel targeted cell therapies is constrained by on-target off-tumor
toxicities, posing significant challenges for safe and effective treatment. To develop …
toxicities, posing significant challenges for safe and effective treatment. To develop …
[PDF][PDF] Latest Insights and Progress in the Clinical Management of Elderly Patients with Acute Myeloid Leukemia: From Genetic Advancements to Targeted Treatments
P NISCOLA, NI Noguera, V Gianfelici, L Cesini… - 2024 - preprints.org
Acute myeloid leukemias (AMLs) are heterogeneous hematologic cancers that occur
prevalently in older patients as the result of a complex pathobiology. The clinical outcomes …
prevalently in older patients as the result of a complex pathobiology. The clinical outcomes …