Harnessing the targeting potential of hyaluronic acid for augmented anticancer activity and safety of duvelisib-loaded nanoparticles in hematological malignancies
Duvelisib (DUV) is effective against numerous hematological malignancies; however, it
suffers from numerous setbacks like poor aqueous solubility, low cellular uptake and …
suffers from numerous setbacks like poor aqueous solubility, low cellular uptake and …
Advancing apoptosis induction in triple negative breast cancer: Empowering treatment with tyrosine-stapled mixed micelles of lapatinib
R Ghadi, A Wadikar, M Dharshini, V Yadav… - Journal of Molecular …, 2024 - Elsevier
The available treatment modalities for triple-negative breast cancer (TNBC) face several
challenges, including discouraging overall survival outcomes, unavoidable toxicities, and …
challenges, including discouraging overall survival outcomes, unavoidable toxicities, and …
Co-Delivery of Glycyrrhizin and Paclitaxel via Gelatin-Based Core–Shell Nanoparticles Ameliorates 1, 2-Dimethylhydrazine-Induced Precancerous Lesions in Colon
Colorectal cancer is a lethal malignancy that begins from acquired/inherent premalignant
lesions. Thus, targeting these lesions at an early stage of the disease could impede the …
lesions. Thus, targeting these lesions at an early stage of the disease could impede the …
Crosslinked hydroxypropyl-β-cyclodextrin nanoparticles for improved efficacy of venetoclax against triple negative breast cancer
Bcl-2 protein plays an integral role in hijacking apoptosis and triggering chemoresistance in
triple negative breast cancer (TNBC). The present study explored the therapeutic efficacy of …
triple negative breast cancer (TNBC). The present study explored the therapeutic efficacy of …
Biotin-stapled mixed micelles of lapatinib: Unleashing apoptosis power in triple-negative breast cancer
The treatment options currently offered for triple-negative breast cancer (TNBC) encounter
numerous obstacles, including disappointing overall survival rates, unavoidable side effects …
numerous obstacles, including disappointing overall survival rates, unavoidable side effects …
Bifunctional Oxaliplatin (IV) Prodrug Based pH-Sensitive PEGylated Liposomes for Synergistic Anticancer Action Against Triple Negative Breast cancer
Triple negative breast cancer (TNBC) exhibits higher susceptibility towards oxaliplatin (OXA)
due to a faulty DNA damage repair system. However, the unfavorable physicochemical …
due to a faulty DNA damage repair system. However, the unfavorable physicochemical …