Anti-depressant properties of crocin molecules in saffron

SA Siddiqui, A Ali Redha, ER Snoeck, S Singh… - Molecules, 2022 - mdpi.com
Saffron is a valued herb, obtained from the stigmas of the C. sativus Linn (Iridaceae), with
therapeutic effects. It has been described in pharmacopoeias to be variously acting …

Medicinal plants used for anxiety, depression, or stress treatment: An update

M Kenda, N Kočevar Glavač, M Nagy… - Molecules, 2022 - mdpi.com
Depression, anxiety, stress, and other mental disorders, which are on the rise worldwide, are
indications that pharmacological therapy can have serious adverse effects, which is why …

[HTML][HTML] Immunoregulatory and anti-inflammatory properties of Crocus sativus (Saffron) and its main active constituents: A review

M Zeinali, MR Zirak, SA Rezaee, G Karimi… - Iranian Journal of …, 2019 - ncbi.nlm.nih.gov
The medicinal uses of saffron, the dried stigmas of Crocus sativus L., have very long history
in food coloring agent, and flavoring agent as well as traditional medicine for the treatment of …

Saffron (Crocus sativus) for depression: a systematic review of clinical studies and examination of underlying antidepressant mechanisms of action

AL Lopresti, PD Drummond - … : Clinical and Experimental, 2014 - Wiley Online Library
Background Saffron, a spice derived from the flower of Crocus sativus, has now undergone
several trials examining its antidepressant effects and, in a recent meta‐analysis, was …

Saffron: a natural product with potential pharmaceutical applications

E Christodoulou, NPE Kadoglou… - Journal of Pharmacy …, 2015 - academic.oup.com
Objectives Recently, a great deal of interest has been developed to isolate and investigate
novel bioactive components from natural resources with health beneficial effects. Saffron is …

Strategies for managing sexual dysfunction induced by antidepressant medication

MJ Taylor, L Rudkin, P Bullemor‐Day… - Cochrane Database …, 2013 - cochranelibrary.com
Background Sexual dysfunction (including altered sexual desire, orgasmic and ejaculatory
dysfunction, erectile and other problems) is a relatively common side effect of antidepressant …

Phytotherapic use of the Crocus sativus L. (Saffron) and its potential applications: A brief overview

S Leone, L Recinella, A Chiavaroli… - Phytotherapy …, 2018 - Wiley Online Library
Crocus sativus L.(Saffron) has long been known for multiple target therapeutic uses. The
plant metabolism is well investigated and the main metabolites related to saffron …

Petals of Crocus sativus L. as a potential source of the antioxidants crocin and kaempferol

K Zeka, KC Ruparelia, MA Continenza, D Stagos… - Fitoterapia, 2015 - Elsevier
Saffron from the province of L'Aquila, in the Abruzzo region of Italy, is highly prized and has
been awarded a formal recognition by the European Union with EU Protected Designation …

Effect of saffron supplementation on symptoms of depression and anxiety: a systematic review and meta-analysis

W Marx, M Lane, T Rocks, A Ruusunen… - Nutrition …, 2019 - academic.oup.com
Abstract Context Saffron (Crocus sativus L.) has gained interest as a potential treatment in
psychiatry. Objective This systematic review and meta-analysis sought to investigate the …

Crocus sativus L. versus citalopram in the treatment of major depressive disorder with anxious distress: a double-blind, controlled clinical trial

A Ghajar, SM Neishabouri, N Velayati… - …, 2017 - thieme-connect.com
Introduction: Saffron (Crocus sativus L.) has demonstrated antidepressant effects in clinical
studies and extensive anxiolytic effects in experimental animal models. Methods: 66 patients …