Molecular biomarkers in cancer

VK Sarhadi, G Armengol - Biomolecules, 2022 - mdpi.com
Molecular cancer biomarkers are any measurable molecular indicator of risk of cancer,
occurrence of cancer, or patient outcome. They may include germline or somatic genetic …

Colorectal liver metastasis: molecular mechanism and interventional therapy

H Zhou, Z Liu, Y Wang, X Wen, EH Amador… - Signal transduction and …, 2022 - nature.com
Colorectal cancer (CRC) is one of the most frequently occurring malignancy tumors with a
high morbidity additionally, CRC patients may develop liver metastasis, which is the major …

Novel diagnostic biomarkers in colorectal cancer

AL Zygulska, P Pierzchalski - International journal of molecular sciences, 2022 - mdpi.com
Colorectal cancer (CRC) is still a leading cause of cancer death worldwide. Less than half of
cases are diagnosed when the cancer is locally advanced. CRC is a heterogenous disease …

Extracellular vesicles and particles impact the systemic landscape of cancer

S Lucotti, CM Kenific, H Zhang, D Lyden - The EMBO journal, 2022 - embopress.org
Intercellular cross talk between cancer cells and stromal and immune cells is essential for
tumor progression and metastasis. Extracellular vesicles and particles (EVPs) are a …

Liquid biopsy: Exosomal microRNAs as novel diagnostic and prognostic biomarkers in cancer

KA Preethi, SC Selvakumar, K Ross, S Jayaraman… - Molecular Cancer, 2022 - Springer
Background Detecting cancer at an early stage before clinical manifestation could be an
effective strategy to decrease cancer mortality. Thus, identifying liquid biopsy biomarkers …

Serum extracellular vesicle-derived circHIPK3 and circSMARCA5 are two novel diagnostic biomarkers for glioblastoma multiforme

M Stella, L Falzone, A Caponnetto, G Gattuso… - Pharmaceuticals, 2021 - mdpi.com
Glioblastoma multiforme (GBM) is the most frequent and deadly human brain cancer. Early
diagnosis through non-invasive biomarkers may render GBM more easily treatable …

Metastasis organotropism in colorectal cancer: advancing toward innovative therapies

K He, Z Wang, M Luo, B Li, N Ding, L Li, B He… - Journal of Translational …, 2023 - Springer
Distant metastasis remains a leading cause of mortality among patients with colorectal
cancer (CRC). Organotropism, referring to the propensity of metastasis to target specific …

Epigenetic landscape of liquid biopsy in colorectal cancer

A Rodriguez-Casanova, N Costa-Fraga… - Frontiers in Cell and …, 2021 - frontiersin.org
Colorectal cancer (CRC) is one of the most common malignancies and is a major cause of
cancer-related deaths worldwide. Thus, there is a clinical need to improve early detection of …

Emerging role of exosomes in retinal diseases

Z Zhang, A Mugisha, S Fransisca, Q Liu… - Frontiers in Cell and …, 2021 - frontiersin.org
Retinal diseases, the leading causes of vison loss and blindness, are associated with
complicated pathogeneses such as angiogenesis, inflammation, immune regulation, fibrous …

[HTML][HTML] MicroRNAs as important contributors in the pathogenesis of colorectal cancer

S Ghafouri-Fard, BM Hussen, E Badrlou, A Abak… - Biomedicine & …, 2021 - Elsevier
Colorectal cancer (CRC) is the third most fatal and fourth most frequently diagnosed
neoplasm in the world. Numerous non-coding RNAs have been shown to contribute in the …