Identifying the earliest-occurring clinically targetable precursors of late-onset Alzheimer's disease
BM Cohen, KC Sonntag - Ebiomedicine, 2024 - thelancet.com
Most cases of Alzheimer's disease (AD) are late-onset dementias (LOAD). However,
research on AD is predominantly of early-onset disease (EOAD). The determinants of EOAD …
research on AD is predominantly of early-onset disease (EOAD). The determinants of EOAD …
CNS/PNS proteoglycans functionalize neuronal and astrocyte niche microenvironments optimizing cellular activity by preserving membrane polarization dynamics …
J Melrose - Journal of Neuroscience Research, 2024 - Wiley Online Library
Central and peripheral nervous system (CNS/PNS) proteoglycans (PGs) have diverse
functional roles, this study examined how these control cellular behavior and tissue function …
functional roles, this study examined how these control cellular behavior and tissue function …
Alzheimer's disease induced neurons bearing PSEN1 mutations exhibit reduced excitability
Alzheimer's disease (AD) is a devastating neurodegenerative condition that affects memory
and cognition, characterized by neuronal loss and currently lacking a cure. Mutations in …
and cognition, characterized by neuronal loss and currently lacking a cure. Mutations in …
Highly efficient Ca 2+ chelation activated by visible light
Calcium ion (Ca2+) control is an essential tool in neuronal research. Herein, we report three
thiocoumarin-based, visible light-activated Ca2+ chelators with quantum yields of 0.39, 0.52 …
thiocoumarin-based, visible light-activated Ca2+ chelators with quantum yields of 0.39, 0.52 …
Familial Alzheimer's Disease Neurons Bearing Mutations in PSEN1 Display Increased Calcium Responses to AMPA as an Early Calcium Dysregulation Phenotype
Familial Alzheimer's disease (FAD) can be caused by mutations in PSEN1 that encode
presenilin-1, a component of the gamma-secretase complex that cleaves amyloid precursor …
presenilin-1, a component of the gamma-secretase complex that cleaves amyloid precursor …
[HTML][HTML] From the Nobel prize for physiology to the new training and competitive paradigm of competitive swimming
A Obradović - Fizička kultura, 2023 - scindeks.ceon.rs
Nitric-monoxide is recognized as a molecule with a very simple structure, considered for a
long time as an extremely toxic substance. Yet, due to the possibility of endogenous …
long time as an extremely toxic substance. Yet, due to the possibility of endogenous …
[PDF][PDF] ОД НОБЕЛОВЕ НАГРАДЕ ЗА ФИЗИОЛОГИЈУ ДО НОВЕ ТРЕНАЖНЕ И ТАКМИЧАРСКЕ ПАРАДИГМЕ СПОРТСКОГ ПЛИВАЊА
А Обрадовић - fizickakultura.com
Сажетак Азот-моноксид је препознат као молекул веома једноставне структуре, дуго
сматран изразито токсичном супстанцом. Ипак, услед могућности ендогене …
сматран изразито токсичном супстанцом. Ипак, услед могућности ендогене …