Viral diseases are one of the leading causes of morbidity and mortality in the world. Virus-
specific vaccines and antiviral drugs are the most powerful tools to combat viral diseases …

Emerging viruses such as HIV, dengue, influenza A, SARS coronavirus, Ebola, and other
viruses pose a significant threat to human health. Majority of these viruses are responsible …

In recent decades, drugs used to treat malaria infection have been shown to be beneficial for
many other diseases, including viral infections. In particular, they have received special …

Infections with flaviviruses, such as dengue, West Nile virus and the recently re-emerging
Zika virus, are an increasing and probably lasting global risk. This Review summarizes and …

Zika virus (ZIKV) infection in utero might lead to microcephaly and other congenital defects.
Since no specific therapy is available thus far, there is an urgent need for the discovery of …

Initially used as antimalarial drugs, hydroxychloroquine (HCQ) and, to a lesser extent,
chloroquine (CQ) are currently being used to treat several diseases. Due to its cost …

Zika virus (ZIKV) infects fetal and adult human brain and is associated with serious
neurological complications. To date, no therapeutic treatment is available to treat ZIKV …

No specific antivirals are currently available for two emerging infectious diseases, Middle
East respiratory syndrome (MERS) and severe acute respiratory syndrome (SARS). A …

Outbreaks of emerging infections, such as COVID-19 pandemic especially, confront health
professionals with the unique challenge of treating patients. With no time to discover new …

Chloroquine (CQ) and its analogue hydroxychloroquine (HCQ) have long been used
worldwide as frontline drugs for the treatment and prophylaxis of human malaria. Since the …