Sex as a biological variable in atherosclerosis

JJ Man, JA Beckman, IZ Jaffe - Circulation research, 2020 - Am Heart Assoc
Atherosclerosis is a chronic inflammatory vascular disease and the predominant cause of
heart attack and ischemic stroke. Despite the well-known sexual dimorphism in the …

The interplay between nonalcoholic fatty liver disease and atherosclerotic cardiovascular disease

AC Finney, S Das, D Kumar, MP McKinney… - Frontiers in …, 2023 - frontiersin.org
Therapeutic approaches that lower circulating low-density lipoprotein (LDL)-cholesterol
significantly reduced the burden of cardiovascular disease over the last decades. However …

Early to sustained impacts of lethal radiation on circulating miRNAs in a minipig model

N Chakraborty, GP Holmes-Hampton, A Gautam… - Scientific Reports, 2023 - nature.com
Early diagnosis of lethal radiation is imperative since its intervention time windows are
considerably short. Hence, ideal diagnostic candidates of radiation should be easily …

Swine disease models for optimal vascular engineering

M Sturek, M Alloosh, FW Sellke - Annual Review of Biomedical …, 2020 - annualreviews.org
Swine disease models are essential for mimicry of human metabolic and vascular
pathophysiology, thereby enabling high-fidelity translation to human medicine. The …

The efficacy of mobile health in alleviating risk factors related to the occurrence and development of coronary heart disease: A systematic review and meta‐analysis

Y Xu, H Ye, Y Zhu, S Du, G Xu, Q Wang - Clinical Cardiology, 2021 - Wiley Online Library
The association between the efficacy of mobile health and the occurrence and development
of coronary heart disease (CHD) is still unclear. Mobile health can alleviate the risk factors …

Differential regulation of brain microvessel transcriptome and brain metabolome by western and heart-healthy dietary patterns in Ossabaw pigs

G Solano-Aguilar, G Matuszek, NR Matthan… - Scientific Reports, 2024 - nature.com
Diet is a potentially modifiable neurodegenerative disease risk factor. We studied the effects
of a typical Western diet (WD; high in refined carbohydrates, cholesterol and saturated fat) …

Hypercholesterolemia-induced HDL dysfunction can be reversed: the impact of diet and statin treatment in a preclinical animal model

L Schoch, P Sutelman, R Suades, L Casani… - International Journal of …, 2022 - mdpi.com
High-density lipoproteins (HDL) undergo adverse remodeling and loss of function in the
presence of comorbidities. We assessed the potential of lipid-lowering approaches (diet and …

High-fidelity porcine models of metabolic syndrome: a contemporary synthesis

GL Cluzel, PM Ryan, FM Herisson… - American Journal of …, 2022 - journals.physiology.org
This review aims to describe and compare porcine models of metabolic syndrome. This
syndrome and its associated secondary comorbidities are set to become the greatest …

Dietary patterns influence epicardial adipose tissue fatty acid composition and inflammatory gene expression in the Ossabaw pig

ME Walker, NR Matthan, A Goldbaum, H Meng… - The Journal of nutritional …, 2019 - Elsevier
Epicardial adipose tissue (EAT) inflammation is implicated in the development and
progression of coronary atherosclerosis. Dietary saturated and polyunsaturated fatty acids …

[HTML][HTML] Accelerated miniature swine models of advanced atherosclerosis: A review based on morphology

D Wang, X Xu, M Zhao, X Wang - Cardiovascular Pathology, 2020 - Elsevier
In order to accelerate development of atherosclerosis (AS) in miniature swine models,
varieties of strategies and methods have been explored. In addition to traditional methods …