The current guideline represents the 6th edition of the “Japanese Clinical Practice Guideline
for Diabetes” which has been revised every three years since its first appearance in 2004 to …

Background The projected rise in the incidence of type 2 diabetes mellitus (T2DM) could
develop into a substantial health problem worldwide. Whether diet, physical activity or both …

Importance Diabetes prevention is imperative to slow worldwide growth of diabetes-related
morbidity and mortality. Yet the long-term efficacy of prevention strategies remains unknown …

Diabetes is a costly disease affecting 387 million individuals globally and 28 million in the
United States. Its precursor, prediabetes, affects 316 and 86 million individuals globally and …

Background The major efficacy trials on diabetes prevention have used resource-intensive
approaches to identify high-risk individuals and deliver lifestyle interventions. Such …

Aim Different intervention strategies can prevent type 2 diabetes (T2DM). Aim of the present
systematic review and meta‐analysis was to evaluate the effectiveness of different …

Objective We aimed to clarify the relationship between serum alanine transaminase (ALT)
levels and incidence of new-onset diabetes in a Japanese general population. Setting …

The prevalence of diabetes mellitus is increasing and is related to sedentary lifestyles and
obesity. Many studies were published on the effect of lifestyle interventions on glucose …

Objective Previous meta-analyses have demonstrated that lifestyle modification can reduce
the blood glucose levels in patients with type 2 diabetes, although the effects of changes in …

Aims Although conventional interventions for people at high risk of developing type 2
diabetes are usually conducted face-to-face, such interventions are burdensome for health …