Severe drought exposure in utero associates to children's epigenetic age acceleration in a global climate change hot spot

X Qiao, B Straight, D Ngo, CE Hilton… - Nature …, 2024 - nature.com
The goal of this study is to examine the association between in utero drought exposure and
epigenetic age acceleration (EAA) in a global climate change hot spot. Calculations of EAA …

Epigenetics in Alzheimer's Disease: A Critical Overview

C Villa, R Combi - International Journal of Molecular Sciences, 2024 - mdpi.com
Epigenetic modifications have been implicated in a number of complex diseases as well as
being a hallmark of organismal aging. Several reports have indicated an involvement of …

Body size, diet quality, and epigenetic aging: cross-sectional and longitudinal analyses

DL Li, AM Hodge, L Cribb, MC Southey… - The Journals of …, 2024 - academic.oup.com
Epigenetic age is an emerging marker of health that is highly predictive of disease and
mortality risk. There is a lack of evidence on whether lifestyle changes are associated with …

DNA methylation clocks for estimating biological age in Chinese cohorts

Z Zheng, J Li, T Liu, Y Fan, QC Zhai, M Xiong… - Protein & …, 2024 - academic.oup.com
Epigenetic clocks are accurate predictors of human chronological age based on the analysis
of DNA methylation (DNAm) at specific CpG sites. However, a systematic comparison …

[HTML][HTML] Epigenetic Signatures of Social Anxiety, Panic Disorders and Stress Experiences: Insights from Genome-wide DNA Methylation Risk Scores

K Ohi, D Fujikane, K Takai, A Kuramitsu, Y Muto… - Psychiatry …, 2024 - Elsevier
Social anxiety disorder (SAD) and panic disorder (PD) are prevalent anxiety disorders
characterized by a complex interplay of genetic and environmental factors. Both disorders …

A combination nutritional supplement reduces DNA methylation age only in older adults with a raised epigenetic age

KC McGee, J Sullivan, J Hazeldine, LJ Schmunk… - GeroScience, 2024 - Springer
An increase in systemic inflammation (inflammaging) is one of the hallmarks of aging.
Epigenetic (DNA methylation) clocks can quantify the degree of biological aging and this …

[HTML][HTML] Characterization of the genetic determinants of context-specific DNA methylation in primary monocytes

JJ Gilchrist, H Fang, S Danielli, M Tomkova, I Nassiri… - Cell Genomics, 2024 - cell.com
To better understand inter-individual variation in sensitivity of DNA methylation (DNAm) to
immune activity, we characterized effects of inflammatory stimuli on primary monocyte …

[HTML][HTML] Vitamins etc, appear to slow down epigenetic aging and reduce inflammation–March 2024

KC McGee, J Sullivan, J Hazeldine, LJ Schmunk… - vitamindwiki.com
An increase in systemic inflammation (inflammaging) is one of the hallmarks of aging.
Epigenetic (DNA methylation) clocks can quantify the degree of biological aging and this …