The remarkable absorption capacity, biodegradability and non-toxicity of lignin
nanoparticles enable them to be appropriate vehicles for drug molecules and inorganic …

Bioactive substances, displaying excellent biocompatibility, chemical stability, and
processability, could be extensively applied in biomedicine and tissue engineering. In recent …

A review of the pharmacological applications of lignins provides evidence of their protective
role against the development of different diseases. In many cases, the effects of lignins could …

Renewable resources are gaining increasing interest as a source for environmentally
benign biomaterials, such as drug encapsulation/release compounds, and scaffolds for …

Natural polymers are recognized for health improvement and, as a consequence, are widely
used in controlled drug delivery, tissue engineering, regenerative medicine, wound …

Lignin is the second most abundant biorenewable polymers only next to cellulose and is
ubiquitous in various plant foods. In food industry, lignin often presented as a major …

Targeting of cancer stem cells (CSC) is expected to be a paradigm-shifting approach for the
treatment of cancers. Cell surface proteoglycans bearing sulfated glycosaminoglycan (GAG) …

Abstract Background Human factor XIa (FXIa) is an actively pursued target for development
of safer anticoagulants. Our long‐standing hypothesis has been that allosterism originating …

Allosteric partial inhibition of soluble, monomeric proteases can offer major regulatory
advantages, but remains a concept on paper to date; although it has been routinely …

Sulfated glycosaminoglycans (GAGs), or synthetic mimetics thereof, are not favorably
viewed as orally bioavailable drugs owing to their high number of anionic sulfate groups …