Brown adipose tissue: physiological function and evolutionary significance

R Oelkrug, ET Polymeropoulos, M Jastroch - Journal of Comparative …, 2015 - Springer
In modern eutherian (placental) mammals, brown adipose tissue (BAT) evolved as a
specialized thermogenic organ that is responsible for adaptive non-shivering thermogenesis …

High-altitude adaptation: mechanistic insights from integrated genomics and physiology

JF Storz - Molecular biology and evolution, 2021 - academic.oup.com
Population genomic analyses of high-altitude humans and other vertebrates have identified
numerous candidate genes for hypoxia adaptation, and the physiological pathways …

Maximal sustained energy budgets in humans and animals

KA Hammond, J Diamond - Nature, 1997 - nature.com
Why are sustained energy budgets of humans and other vertebrates limited to not more than
about seven times resting metabolic rate? The answer to this question has potential …

[PDF][PDF] Evolutionary physiology

T Garland, PA Carter - Annual review of physiology, 1994 - as.uky.edu
" The objectives of comparative physiology are:(1) to describe the diverse ways which
different kinds of animals meet their functional requirements;(2) to elucidate evolutionary …

Intensity-controlled treadmill running in mice: cardiac and skeletal muscle hypertrophy

OJ Kemi, JP Loennechen, U Wisløff… - Journal of applied …, 2002 - journals.physiology.org
Whereas novel pathways of pathological heart enlargement have been unveiled by thoracic
aorta constriction in genetically modified mice, the molecular mechanisms of adaptive …

An analysis of the factors that influence the level and scaling of mammalian BMR

BK McNab - Comparative Biochemistry and Physiology Part A …, 2008 - Elsevier
The factors influencing the basal rate of metabolism (BMR) in 639 species of mammals
include body mass, food habits, climate, habitat, substrate, a restriction to islands or …

The cost of living: field metabolic rates of small mammals

JR Speakman - Advances in ecological research, 1999 - Elsevier
Publisher Summary The chapter begins with an overview of cost of living based on field
metabolic rates of small mammals. The chapter then goes on to discuss the importance of …

Determinants of inter-specific variation in basal metabolic rate

CR White, MR Kearney - Journal of Comparative physiology B, 2013 - Springer
Basal metabolic rate (BMR) is the rate of metabolism of a resting, postabsorptive, non-
reproductive, adult bird or mammal, measured during the inactive circadian phase at a …

Physiological differentiation of vertebrate populations

T Garland Jr, SC Adolph - Annual Review of Ecology and Systematics, 1991 - JSTOR
Physiological Differentiation of Vertebrate Populations Page 1 Annu. Rev. Ecol. Syst. 1991.
22:193-228 Copyright ? 1991 by Annual Reviews Inc. All rights reserved PHYSIOLOGICAL …

Regulatory changes contribute to the adaptive enhancement of thermogenic capacity in high-altitude deer mice

ZA Cheviron, GC Bachman… - Proceedings of the …, 2012 - National Acad Sciences
In response to hypoxic stress, many animals compensate for a reduced cellular O2 supply
by suppressing total metabolism, thereby reducing O2 demand. For small endotherms that …