[HTML][HTML] Cytokines in atherosclerosis: Key players in all stages of disease and promising therapeutic targets
Atherosclerosis, a chronic inflammatory disorder of the arteries, is responsible for most
deaths in westernized societies with numbers increasing at a marked rate in developing …
deaths in westernized societies with numbers increasing at a marked rate in developing …
Interactions between inflammation and lipid metabolism: relevance for efficacy of anti-inflammatory drugs in the treatment of atherosclerosis
JA van Diepen, JFP Berbée, LM Havekes… - Atherosclerosis, 2013 - Elsevier
Dyslipidemia and inflammation are well known causal risk factors the development of
atherosclerosis. The interplay between lipid metabolism and inflammation at multiple levels …
atherosclerosis. The interplay between lipid metabolism and inflammation at multiple levels …
Delivery of MicroRNAs by Chitosan Nanoparticles to Functionally Alter Macrophage Cholesterol Efflux in Vitro and in Vivo
MA Nguyen, H Wyatt, L Susser, M Geoffrion… - ACS …, 2019 - ACS Publications
The prevention and treatment of cardiovascular diseases (CVD) has largely focused on
lowering circulating LDL cholesterol, yet a significant burden of atherosclerotic disease …
lowering circulating LDL cholesterol, yet a significant burden of atherosclerotic disease …
[HTML][HTML] The cholesterol metabolite 27-hydroxycholesterol promotes atherosclerosis via proinflammatory processes mediated by estrogen receptor alpha
M Umetani, P Ghosh, T Ishikawa, J Umetani, M Ahmed… - Cell metabolism, 2014 - cell.com
Oxysterols are cholesterol metabolites that serve multiple functions in lipid metabolism,
including as liver X receptor (LXR) ligands. 27-hydroxycholesterol (27HC) is an abundant …
including as liver X receptor (LXR) ligands. 27-hydroxycholesterol (27HC) is an abundant …
[HTML][HTML] The influence of dysfunctional signaling and lipid homeostasis in mediating the inflammatory responses during atherosclerosis
ML Buckley, DP Ramji - Biochimica et Biophysica Acta (BBA)-Molecular …, 2015 - Elsevier
Atherosclerosis, the underlying cause of myocardial infarction and thrombotic
cerebrovascular events, is responsible for the majority of deaths in westernized societies …
cerebrovascular events, is responsible for the majority of deaths in westernized societies …
Liver X receptor activation increases hepatic fatty acid desaturation by the induction of SCD1 expression through an LXR α‐SREBP1c‐dependent mechanism (肝X 受 …
X Zhang, J Liu, W Su, J Wu, C Wang, X Kong… - Journal of …, 2014 - Wiley Online Library
摘要背景肝X 受体(liver X receptors, LXRs) 包括LXRα 和LXRβ 属于核激素受体超家族成员,
是配体依赖的转录调节因子, 目前已知LXR 在体内作为脂质感受器, 参与了一系列胆固醇和 …
是配体依赖的转录调节因子, 目前已知LXR 在体内作为脂质感受器, 参与了一系列胆固醇和 …
Gene therapy for cardiovascular disease: basic research and clinical prospects
G Cao, X Xuan, R Zhang, J Hu, H Dong - Frontiers in cardiovascular …, 2021 - frontiersin.org
In recent years, the vital role of genetic factors in human diseases have been widely
recognized by scholars with the deepening of life science research, accompanied by the …
recognized by scholars with the deepening of life science research, accompanied by the …
Oxy210, a semi-synthetic oxysterol, exerts anti-inflammatory effects in macrophages via inhibition of toll-like receptor (TLR) 4 and TLR2 signaling and modulation of …
F Wang, F Stappenbeck, LY Tang, YE Zhang… - International journal of …, 2022 - mdpi.com
Inflammatory responses by the innate and adaptive immune systems protect against
infections and are essential to health and survival. Many diseases including atherosclerosis …
infections and are essential to health and survival. Many diseases including atherosclerosis …
[HTML][HTML] Dihomo-γ-linolenic acid inhibits several key cellular processes associated with atherosclerosis
H Gallagher, JO Williams, N Ferekidis, A Ismail… - … et Biophysica Acta (BBA …, 2019 - Elsevier
Atherosclerosis and its complications are responsible for one in three global deaths.
Nutraceuticals show promise in the prevention and treatment of atherosclerosis but require …
Nutraceuticals show promise in the prevention and treatment of atherosclerosis but require …
Atherogenesis: hyperhomocysteinemia interactions with LDL, macrophage function, paraoxonase 1, and exercise
I Chernyavskiy, S Veeranki, U Sen… - Annals of the new York …, 2016 - Wiley Online Library
Despite great strides in understanding the atherogenesis process, the mechanisms are not
entirely known. In addition to diet, cigarette smoking, genetic predisposition, and …
entirely known. In addition to diet, cigarette smoking, genetic predisposition, and …