The approval of immune checkpoint inhibitors (ICIs) by the Food and Drug Administration
(FDA) led to an improvement in the treatment of several types of cancer. The main targets of …

Poor recovery of neuronal functions is one of the most common healthcare challenges for
patients with different types of brain injuries and/or neurodegenerative diseases …

Background Reprogramming human induced pluripotent stem cells (iPSCs) from somatic
cells and generating three-dimensional brain organoids from these iPSCs provide access to …

Parkinson's disease (PD) is one of the most common neurodegenerative diseases with the
characteristics of a progressive loss of dopaminergic neurons. Biomaterials employed in the …

Pneumococcal meningitis, inflammation of the meninges due to an infection of the Central
Nervous System caused by Streptococcus pneumoniae (the pneumococcus), is the most …

Background Long period of SARS-CoV-2 infection has been associated with psychiatric and
cognitive disorders in adolescents and children. SARS-CoV-2 remains dormant in the CNS …

The physiological and pathological properties of the neural germinal stem cell niche have
been well-studied in the past 30 years, mainly in animals and within given limits in humans …

Background Many of the motor symptoms of Parkinson's disease (PD) impact quality of life
and are not fully ameliorated by current pharmacological and surgical treatments. A better …

Effective communication between different cell types is essential for brain health, and
dysregulation of this process leads to neuropathologies. Brain glial cells, including microglia …

Simple Summary According to the stem cell theory of cancer, we should be judicious with
immunotherapy in cancer care. When we do not realize that cancer originates from a stem …