At implantation, the embryo expresses paternally derived alloantigens and evokes
inflammation that can threaten reproductive success. To ensure a robust placenta and …

Recurrent pregnancy loss (RPL) represents an unresolved problem for contemporary
gynecology and obstetrics. In fact, it is not only a relevant complication of pregnancy, but is …

Immune cells are essential for endometrial receptivity to embryo implantation and early
placental development. They exert tissue-remodeling and immune regulatory roles—acting …

Alzheimer's disease (AD) is the most common form of dementia, characterized by
progressive degeneration and loss of neurons in specific regions of the central nervous …

Recurrent pregnancy loss (RPL) is a common and severe pathological pregnancy, whose
pathogenesis is not fully understood. With the development of epigenetics, the study of DNA …

ZEB1 and ZEB2 are zinc-finger E homeobox-binding transcription factors best known for
their role in driving epithelial to mesenchymal transition. However, in recent years our …

Inflammation is a central feature and is implicated as a causal factor in preeclampsia and
other hypertensive disorders of pregnancy. Inflammatory mediators and leukocytes, which …

A wide variety and large number of bacterial species live in the gut, forming the gut
microbiota. Gut microbiota not only coexist harmoniously with their hosts, but they also …

Immunotherapy has shown promising anti-tumor effects across various tumors, yet it
encounters challenges from the inhibitory tumor immune microenvironment (TIME) …

Regulatory T (Treg) cells maintain immune homeostasis by preventing abnormal or
excessive immune responses. Histone deacetylase 6 (HDAC6) regulates expression of …