Mesenchymal stem/stromal cells as a valuable source for the treatment of immune-mediated disorders

A Markov, L Thangavelu, S Aravindhan… - Stem cell research & …, 2021 - Springer
Over recent years, mesenchymal stem/stromal cells (MSCs) and their potential biomedical
applications have received much attention from the global scientific community in an …

Mesenchymal stem cells: amazing remedies for bone and cartilage defects

P Kangari, T Talaei-Khozani… - Stem Cell Research & …, 2020 - Springer
Skeletal disorders are among the leading debilitating factors affecting millions of people
worldwide. The use of stem cells for tissue repair has raised many promises in various …

Mesenchymal stromal cell-based therapy for cartilage regeneration in knee osteoarthritis

XN Xiang, SY Zhu, HC He, X Yu, Y Xu… - Stem cell research & …, 2022 - Springer
Osteoarthritis, as a degenerative disease, is a common problem and results in high
socioeconomic costs and rates of disability. The most commonly affected joint is the knee …

[HTML][HTML] Harnessing knee joint resident mesenchymal stem cells in cartilage tissue engineering

X Xu, L Xu, J Xia, C Wen, Y Liang, Y Zhang - Acta Biomaterialia, 2023 - Elsevier
Osteoarthritis (OA) is a widespread clinical disease characterized by cartilage degeneration
in middle-aged and elderly people. Currently, there is no effective treatment for OA apart …

Heterogeneity of mesenchymal stem cells in cartilage regeneration: from characterization to application

K Zha, X Li, Z Yang, G Tian, Z Sun, X Sui… - NPJ Regenerative …, 2021 - nature.com
Articular cartilage is susceptible to damage but hard to self-repair due to its avascular
nature. Traditional treatment methods are not able to produce satisfactory effects …

Clinical utility of mesenchymal stem/stromal cells in regenerative medicine and cellular therapy

VV Maldonado, NH Patel, EE Smith, CL Barnes… - Journal of biological …, 2023 - Springer
Mesenchymal stem/stromal cells (MSCs) have been carefully examined to have tremendous
potential in regenerative medicine. With their immunomodulatory and regenerative …

Adipose‐Derived stem cells: current applications and future directions in the regeneration of multiple tissues

J Zhang, Y Liu, Y Chen, L Yuan, H Liu… - Stem Cells …, 2020 - Wiley Online Library
Adipose‐derived stem cells (ADSCs) can maintain self‐renewal and enhanced
multidifferentiation potential through the release of a variety of paracrine factors and …

Engineering exosomes derived from subcutaneous fat MSCs specially promote cartilage repair as miR-199a-3p delivery vehicles in Osteoarthritis

S Zhao, G Xiu, J Wang, Y Wen, J Lu, B Wu… - Journal of …, 2023 - Springer
Osteoarthritis (OA) is a degenerative joint disease involving cartilage. Exosomes derived
from Mesenchymal stem cells (MSCs) therapy improves articular cartilage repair, but …

Research progress in the use of mesenchymal stem cells and their derived exosomes in the treatment of osteoarthritis

H Yu, Y Huang, L Yang - Ageing research reviews, 2022 - Elsevier
Osteoarthritis (OA), as a common orthopedic disease with cartilage injury as its main
pathological feature, has a complex pathogenesis and existing medical technology remains …

Treatment of knee osteoarthritis with intra-articular injection of autologous adipose-derived mesenchymal progenitor cells: a prospective, randomized, double-blind …

L Lu, C Dai, Z Zhang, H Du, S Li, P Ye, Q Fu… - Stem cell research & …, 2019 - Springer
Objective Human adipose-derived mesenchymal progenitor cells (haMPCs) are stem cells
with multiple differentiation potential and immunomodulatory function. Re-Join® comprises …