The inclusion of'the anti-DNA antibody'by the ACR and the Systemic Lupus International
Collaborating Clinics (SLICC) as a criterion for systemic lupus erythematosus does not …

Systemic lupus erythematosus (SLE) is an autoimmune syndrome characterized by
autoantibodies to nuclear constituents. Some of these antibodies are diagnostically …

Background: The presence of “anti-DNA antibodies in abnormal titres” is a well established
criterion for SLE classification, but there is no agreement on the performance of this test …

One cannot discuss anti-dsDNA antibodies and lupus nephritis without discussing the
nature of Systemic lupus erythematosus (SLE). SLE is insistently described as a prototype …

Systemic lupus erythematosus is an inflammatory autoimmune syndrome of unknown cause.
Kidney disease is a central and serious complication in this syndrome. Deposition of …

Objective The aim of this study was to assess whether circulating histone‐specific T cells
represent tools for precision medicine in systemic lupus erythematosus (SLE). Methods …

Murine and human systemic lupus erythematosus (SLE, lupus) is characterized by the
appearance of autoantibodies directed to nuclear and cell membrane phospholipid …

Summary CD4+ CD25+ regulatory T cells have been shown to be a vital component of the
mechanisms that prevent autoreactivity in mice and also in humans. Previous studies have …

Autoantibodies are key mediators in determining the clinical manifestations of systemic
lupus erythematosus (SLE). The mechanisms by which antibodies may be harmful to self …

Antibodies that are directed against components of the cell nucleus almost always
accompany systemic lupus erythematosus (SLE). Formation of antibodies against double …