Sickle cell syndromes, including sickle cell disease (SCD) and sickle cell trait, are
associated with multiple kidney abnormalities. Young patients with SCD have elevated …

The number of individuals with the sickle cell trait exceeds 300 million worldwide, making
sickle cell disease one of the most common monogenetic diseases globally. Because of the …

Sickle cell trait (SCT) is the carrier state for sickle cell disease that results from the HBB
rs334 missense mutation (p. Glu6Val) in the β‐globin chain of haemoglobin. While not …

Results We identified 8968 reference patients, 1279 patients with sickle cell trait, and 254
patients with sickle cell disease with a median follow-up of 7.6 years and mean baseline …

Sickle cell trait (SCT) is the benign heterozygous carrier state for the sickle variant of the
HBB gene. Most of the~ 300 million people with SCT worldwide will not experience any …

Rationale & Objective Few studies have investigated racial disparities in acute kidney injury
(AKI), in contrast to the extensive literature on racial differences in the risk of kidney failure …

Study Design: Prospective cohort study Setting & Participants: We studied 2720 self-
identified Black or White participants in the Chronic Renal Insufficiency Cohort study from …

BACKGROUND: Acute kidney injury (AKI) in coronavirus disease-19 (COVID-19) has high
incidence and mortality. Risk factors for AKI in COVID-19 patients are not well explored. This …

Anemia is a condition characterized by too few red blood cells, leading to diminished
oxygen delivery, which can significantly impact exercise participation and athletic …

Clinical Question: During bouts of exercises in a hypohydrated state, do patients with sickle
cell trait compared with patients without sickle cell trait demonstrate higher blood viscosity …