Brain oxytocin: how puzzle stones from animal studies translate into psychiatry

V Grinevich, ID Neumann - Molecular psychiatry, 2021 - nature.com
The neuropeptide oxytocin has attracted great attention of the general public, basic
neuroscience researchers, psychologists, and psychiatrists due to its profound pro-social …

The effects of oxytocin on appetite regulation, food intake and metabolism in humans

L Kerem, EA Lawson - International Journal of Molecular Sciences, 2021 - mdpi.com
The hypothalamic peptide oxytocin and its receptor are involved in a range of physiological
processes, including parturition, lactation, cell growth, wound healing, and social behavior …

Social touch promotes interfemale communication via activation of parvocellular oxytocin neurons

Y Tang, D Benusiglio, A Lefevre, L Hilfiger… - Nature …, 2020 - nature.com
Oxytocin (OT) is a great facilitator of social life but, although its effects on socially relevant
brain regions have been extensively studied, OT neuron activity during actual social …

Social anxiety disorder-associated gut microbiota increases social fear

NL Ritz, M Brocka, MI Butler… - Proceedings of the …, 2024 - National Acad Sciences
Social anxiety disorder (SAD) is a crippling psychiatric disorder characterized by intense
fear or anxiety in social situations and their avoidance. However, the underlying biology of …

Labeled oxytocin administered via the intranasal route reaches the brain in rhesus macaques

MR Lee, TA Shnitko, SW Blue, AV Kaucher… - Nature …, 2020 - nature.com
Oxytocin may have promise as a treatment for neuropsychiatric disorders. Its therapeutic
effect may depend on its ability to enter the brain and bind to the oxytocin receptor. To date …

The multiple faces of the oxytocin and vasopressin systems in the brain

V Grinevich, M Ludwig - Journal of neuroendocrinology, 2021 - Wiley Online Library
Classically, hypothalamic neuroendocrine cells that synthesise oxytocin and vasopressin
were categorised in two major cell types: the magnocellular and parvocellular neurones. It …

Oxytocin promotes prefrontal population activity via the PVN-PFC pathway to regulate pain

Y Liu, A Li, C Bair-Marshall, H Xu, HJ Jee, E Zhu… - Neuron, 2023 - cell.com
Neurons in the prefrontal cortex (PFC) can provide top-down regulation of sensory-affective
experiences such as pain. Bottom-up modulation of sensory coding in the PFC, however …

Peptidergic and functional delineation of the Edinger-Westphal nucleus

MF Priest, SN Freda, IJ Rieth, D Badong… - Cell reports, 2023 - cell.com
Many neuronal populations that release fast-acting excitatory and inhibitory
neurotransmitters in the brain also contain slower-acting neuropeptides. These facultative …

Links between the neurobiology of oxytocin and human musicality

AR Harvey - Frontiers in human neuroscience, 2020 - frontiersin.org
The human species possesses two complementary, yet distinct, universal communication
systems—language and music. Functional imaging studies have revealed that some core …

Oxytocin-based therapies for treatment of Prader-Willi and Schaaf-Yang syndromes: evidence, disappointments, and future research strategies

F Althammer, F Muscatelli, V Grinevich… - Translational …, 2022 - nature.com
The prosocial neuropeptide oxytocin is being developed as a potential treatment for various
neuropsychiatric disorders including autism spectrum disorder (ASD). Early studies using …