Methanotrophs: discoveries, environmental relevance, and a perspective on current and future applications

S Guerrero-Cruz, A Vaksmaa, MA Horn… - Frontiers in …, 2021 - frontiersin.org
Methane is the final product of the anaerobic decomposition of organic matter. The
conversion of organic matter to methane (methanogenesis) as a mechanism for energy …

Engineered methanotrophy: a sustainable solution for methane-based industrial biomanufacturing

AD Nguyen, EY Lee - Trends in Biotechnology, 2021 - cell.com
Methane is a promising feedstock with high abundance and low cost for the sustainable
production of biochemicals and biofuels. Methanotrophic bacteria are particularly interesting …

Use of rare‐earth elements in the phyllosphere colonizer Methylobacterium extorquens PA1

AM Ochsner, L Hemmerle, T Vonderach… - Molecular …, 2019 - Wiley Online Library
Until recently, rare‐earth elements (REEs) had been thought to be biologically inactive. This
view changed with the discovery of the methanol dehydrogenase XoxF that strictly relies on …

C1-based biomanufacturing: Advances, challenges and perspectives

X Lv, W Yu, C Zhang, P Ning, J Li, Y Liu, G Du… - Bioresource …, 2023 - Elsevier
Abstract One-carbon (C1) compounds have emerged as a key research focus due to the
growth of metabolic engineering and synthetic biology as affordable and sustainable …

Engineering the metabolic landscape of microorganisms for lignocellulosic conversion

JM Peña-Castro, KM Muñoz-Páez… - Microorganisms, 2023 - mdpi.com
Bacteria and yeast are being intensively used to produce biofuels and high-added-value
products by using plant biomass derivatives as substrates. The number of microorganisms …

Genome-scale evaluation of core one-carbon metabolism in gammaproteobacterial methanotrophs grown on methane and methanol

AD Nguyen, JY Park, IY Hwang, R Hamilton… - Metabolic …, 2020 - Elsevier
Methylotuvimicrobium alcaliphilum 20Z is a promising platform strain for bioconversion of
one-carbon (C1) substrates into value-added products. To carry out robust metabolic …

Outlook on engineering methylotrophs for one-carbon-based industrial biotechnology

DN Pham, AD Nguyen, EY Lee - Chemical Engineering Journal, 2022 - Elsevier
Methane and carbon dioxide (CO 2) account for the most abundant greenhouse gases
(GHGs). The removal of atmospheric methane and CO 2 is an urgent mission contributing to …

Engineering type I methanotrophic bacteria as novel platform for sustainable production of 3-hydroxybutyrate and biodegradable polyhydroxybutyrate from methane …

THT Chau, AD Nguyen, EY Lee - Bioresource Technology, 2022 - Elsevier
Methylotuvimicrobium alcaliphilum 20Z recombinant strain co-utilizing methane and xylose
from anthropogenic activities and lignocellulose biomass is a promising cell factory platform …

Methanotrophic microbial cell factory platform for simultaneous conversion of methane and xylose to value-added chemicals

AD Nguyen, THT Chau, EY Lee - Chemical Engineering Journal, 2021 - Elsevier
Biotechnological production of value-added products from sustainable resources such as
C1 gas and lignocellulosic biomass is a practical solution for sustainable manufacturing …

Core Metabolism Shifts during Growth on Methanol versus Methane in the Methanotroph Methylomicrobium buryatense 5GB1

Y Fu, L He, J Reeve, DAC Beck, ME Lidstrom - MBio, 2019 - Am Soc Microbiol
Methylomicrobium buryatense 5GB1 is an obligate methylotroph which grows on methane
or methanol with similar growth rates. It has long been assumed that the core metabolic …