The aging and elderly population are particularly susceptible to cardiovascular disease. Age
is an independent risk factor for cardiovascular disease (CVD) in adults, but these risks are …

Purpose Severe community-acquired pneumonia (SCAP) is still associated with substantial
morbidity and mortality. In this point-of-view review paper, a group of experts discuss the …

Background Invasive mechanical ventilation in critically ill adults involves adjusting the
fraction of inspired oxygen to maintain arterial oxygen saturation. The oxygen-saturation …

Objective: Decades-old, common ICU practices including deep sedation, immobilization,
and limited family access are being challenged. We endeavoured to evaluate the …

The world is scrutinizing every cohort and every outcome for patients with coronavirus
disease (COVID-19), particularly the most critically ill who are receiving mechanical …

Purpose To describe critical care patients with COVID-19 across England, Wales and
Northern Ireland and compare them with a historic cohort of patients with other viral …

Introduction Despite evidence demonstrating the value of performance initiatives, marked
differences remain between hospitals in the delivery of care for patients with sepsis. The …

Importance Tracheostomy is a widely used intervention in adult critical care units. There is
little evidence to guide clinicians regarding the optimal timing for this procedure. Objective …

Purpose To quantify the numbers of critical care beds in Europe and to understand the
differences in these numbers between countries when corrected for population size and …

Background Mortality from severe sepsis and septic shock differs across continents,
countries, and regions. We aimed to use data from the Surviving Sepsis Campaign (SSC) to …