Natural product research aims to characterize specialized metabolites from various living organisms and assess their biological properties from either a chemical ecology or drug …
T Netzker, J Fischer, J Weber, DJ Mattern… - Frontiers in …, 2015 - frontiersin.org
Microorganisms form diverse multispecies communities in various ecosystems. The high abundance of fungal and bacterial species in these consortia results in specific …
Endophytic fungi became an attractive source for the discovery of new leads, because of the complexity and the structural diversity of their secondary metabolites. The genus Fusarium …
D Arora, P Gupta, S Jaglan, C Roullier, O Grovel… - Biotechnology …, 2020 - Elsevier
Natural products (NPs) are considered as a cornerstone for the generation of bioactive leads in drug discovery programs. However, one of the major limitations of NP drug discovery …
RV Kapoore, G Padmaperuma, S Maneein… - Critical Reviews in …, 2022 - Taylor & Francis
The application of microbial co-cultures is now recognized in the fields of biotechnology, ecology, and medicine. Understanding the biological interactions that govern the …
L Guo, B Xi, L Lu - Bioresource Technology, 2024 - Elsevier
Increasing evidence shows that microbial synthesis plays an important role in producing high value-added products. However, microbial monoculture generally hampers metabolites …
In natural product research, microbial metabolites have tremendous potential to provide new therapeutic agents since extremely diverse chemical structures can be found in the nearly …
DJ Newman, GM Cragg - Planta medica, 2020 - thieme-connect.com
In the last 20 or so years, the influence of endophytes and, quite recently, epiphytes of plants upon the compounds found in those plants, which were usually assumed to be …
DJ Newman, GM Cragg - Frontiers in chemistry, 2015 - frontiersin.org
Beginning with the report by Stierle and Strobel in 1993 on taxol (R) production by an endophytic fungus (Stierle et al.,), it is possible that a number of the agents now used as …