Brain function critically depends on a close matching between metabolic demands,
appropriate delivery of oxygen and nutrients, and removal of cellular waste. This matching …

The Japanese Society of Hypertension (JSH) revised the Guidelines for the Management of
Hypertension 2014 (JSH 2014), and published the JSH 2019. In the development of the JSH …

We present a review of the characterization of healthy brain aging using MRI with an
emphasis on morphology, lesions, and quantitative MR parameters. A scope review found …

Benetos et al Management of Hypertension in the Very Old 821 requires the duration of
benefit to be determined. Finally, the 2013 ESH/ESC guidelines state that the HYVET …

Velocity-selective inversion (VSI) based velocity-selective arterial spin labeling (VSASL) has
been developed to measure cerebral blood flow (CBF) with low susceptibility to the …

Importance Little is known about the associations of strict blood pressure (BP) control with
microstructural changes in small vessel disease markers. Objective To investigate the …

Opinion statement Cerebral small vessel disease (SVD) is characterised by damage to deep
grey and white matter structures of the brain and is responsible for a diverse range of clinical …

Cerebral autoregulation and baroreflex sensitivity are key mechanisms that maintain
cerebral blood flow. This study assessed whether these control mechanisms are affected in …

Alzheimer's disease (AD) is the most common form of dementia. With an aging population
and no disease modifying treatments available, AD is quickly becoming a global pandemic …

Artery remodeling, described as a change in artery structure, may be responsible for the
increased risk of cardiovascular disease with aging. Although the risk for stroke is known to …