[HTML][HTML] Calcium carbonate vaterite particles for drug delivery: Advances and challenges

DB Trushina, TN Borodina, S Belyakov… - Materials Today …, 2022 - Elsevier
The recent successful application of lipid-based nanoparticles as delivery vehicles in COVID-
19 vaccines demonstrated the superior potential of nanoparticle-based technology for …

Engineered drug delivery nanosystems for tumor microenvironment normalization therapy

B Yang, F Meng, J Zhang, K Chen, S Meng, K Cai… - Nano Today, 2023 - Elsevier
As a complex" soil" ecosystem, the tumor microenvironment (TME) plays a crucial role in the
occurrence, development and metastasis of tumors. Reprogramming TME can block the …

Chemical Modulation of Glucose Metabolism with a Fluorinated CaCO3 Nanoregulator Can Potentiate Radiotherapy by Programming Antitumor Immunity

Z Dong, C Wang, Y Gong, Y Zhang, Q Fan, Y Hao… - ACS …, 2022 - ACS Publications
Tumor hypoxia and acidity are well-known features in solid tumors that cause
immunosuppression and therapeutic resistance. Herein, we rationally synthesized a …

Recent nanotechnological interventions targeting PI3K/Akt/mTOR pathway: a focus on breast cancer

VR Sharma, AK Sharma, V Punj, P Priya - Seminars in cancer biology, 2019 - Elsevier
Breast cancer is the major cause of deaths in women worldwide. Detection and treatment of
breast cancer at earlier stages of the disease has shown encouraging results. Modern …

Recent progress in nanocarrier-based drug delivery systems for antitumour metastasis

S Peng, X Yuan, H Li, Y Wei, B Zhou, G Ding… - European Journal of …, 2023 - Elsevier
Tumour metastasis is one of the major factors leading to poor prognosis as well as lower
survival among cancer patients. A number of studies investigating the inhibition of tumour …

Construction of pH‐Sensitive Nanovaccines Encapsulating Tumor Cell Lysates and Immune Adjuvants for Breast Cancer Therapy

Y Ding, J Yang, H Wei, J Wang, S Huang, S Yang… - Small, 2023 - Wiley Online Library
The current immunotherapy strategies for triple negative breast cancer (TNBC) are greatly
limited due to the immunosuppressive tumor microenvironment (TME). Immunization with …

[HTML][HTML] The reversed intra-and extracellular pH in tumors as a unified strategy to chemotherapeutic delivery using targeted nanocarriers

E Pérez-Herrero, A Fernández-Medarde - Acta Pharmaceutica Sinica B, 2021 - Elsevier
Solid tumors are complex entities, comprising a wide variety of malignancies with very
different molecular alterations. Despite this, they share a set of characteristics known as …

Eco-friendly processes for the synthesis of amorphous calcium carbonate nanoparticles in ethanol and their stabilisation in aqueous media

L Chuzeville, F Boury, D Duday, R Anand, E Moretto… - Green …, 2022 - pubs.rsc.org
Amorphous calcium carbonate nanoparticles (ACC NPs) are promising multifunctional
materials for healthcare applications. Due to their instability in aqueous media, pure ACC …

[HTML][HTML] Cellular Investigations on Mechanistic Biocompatibility of Green Synthesized Calcium Oxide Nanoparticles with Danio rerio

R Eram, P Kumari, PK Panda, S Singh… - Journal of …, 2021 - mdpi.com
The utility of calcium oxide nanoparticles in the biomedical and physical fields has instigated
their biocompatible synthesis and production. Moreover, it is important to investigate their …

Tumor microenvironment modulating functional nanoparticles for effective cancer treatments

S Shin, J Lee, J Han, F Li, D Ling, W Park - Tissue Engineering and …, 2022 - Springer
Cancer is one of the major diseases that threaten human life worldwide. Despite advances
in cancer treatment techniques, such as radiation therapy, chemotherapy, targeted therapy …