Cells are programmed to favorably respond towards the nutrient availability by adapting
their metabolism to meet energy demands. AMP-activated protein kinase (AMPK) is a highly …

AMP-activated protein kinase (AMPK) is known as a pivotal cellular energy sensor,
mediating the adaptation to low energy levels by deactivating anabolic processes and …

Panax ginseng and Panax notoginseng, two well-known medical plants with economic
value, have a long history of use for managing various diseases in Asian countries …

Acetyl-CoA is a metabolite at the crossroads of central metabolism and the substrate of
histone acetyltransferases regulating gene expression. In many tissues fasting or lifespan …

Heart failure is one of the leading causes of death and disability worldwide. Left ventricle
remodeling, fibrosis, and ischemia/reperfusion injury all contribute to the deterioration of …

Metformin (MF), a first-line drug to treat type 2 diabetes mellitus (T2DM), alone and in
combination with other drugs, restores the ovarian function in women with polycystic ovary …

Obesity is becoming a pandemic, and its prevalence is still increasing. Considering that
obesity increases the risk of developing cardiometabolic diseases, research efforts are …

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First seen as a fat-storage tissue, the adipose tissue is considered as a critical player in the
endocrine system. Precisely, adipose tissue can produce an array of bioactive factors …

Adiponectin is the adipokine associated with insulin sensitization, reducing liver
gluconeogenesis, and increasing fatty acid oxidation and glucose uptake. Adiponectin is …