Ventral tegmental area: cellular heterogeneity, connectivity and behaviour

M Morales, EB Margolis - Nature Reviews Neuroscience, 2017 - nature.com
Dopamine-releasing neurons of the ventral tegmental area (VTA) have central roles in
reward-related and goal-directed behaviours. VTA dopamine-releasing neurons are …

The nucleus accumbens: mechanisms of addiction across drug classes reflect the importance of glutamate homeostasis

MD Scofield, JA Heinsbroek, CD Gipson… - Pharmacological …, 2016 - Elsevier
The nucleus accumbens is a major input structure of the basal ganglia and integrates
information from cortical and limbic structures to mediate goal-directed behaviors. Chronic …

Anatomy and function of ventral tegmental area glutamate neurons

J Cai, Q Tong - Frontiers in neural circuits, 2022 - frontiersin.org
The ventral tegmental area (VTA) is well known for regulating reward consumption, learning,
memory, and addiction behaviors through mediating dopamine (DA) release in downstream …

Synaptic and circuit functions of multitransmitter neurons in the mammalian brain

ML Wallace, BL Sabatini - Neuron, 2023 - cell.com
Neurons in the mammalian brain are not limited to releasing a single neurotransmitter but
often release multiple neurotransmitters onto postsynaptic cells. Here, we review recent …

Optogenetic investigation of neural circuits underlying brain disease in animal models

KM Tye, K Deisseroth - Nature Reviews Neuroscience, 2012 - nature.com
Optogenetic tools have provided a new way to establish causal relationships between brain
activity and behaviour in health and disease. Although no animal model captures human …

[图书][B] Behavior analysis and learning: A biobehavioral approach

WD Pierce, CD Cheney - 2017 - taylorfrancis.com
Using a consistent Skinnerian perspective, Behavior Analysis and Learning: A
Biobehavioral Approach, Sixth Edition provides an advanced introduction to the principles of …

Dissecting the diversity of midbrain dopamine neurons

J Roeper - Trends in neurosciences, 2013 - cell.com
Midbrain dopamine (DA) neurons are essential for controlling key functions of the brain,
such as voluntary movement, reward processing, and working memory. The largest …

VTA glutamate neuron activity drives positive reinforcement absent dopamine co-release

V Zell, T Steinkellner, NG Hollon, SM Warlow, E Souter… - Neuron, 2020 - cell.com
Like ventral tegmental area (VTA) dopamine (DA) neurons, VTA glutamate neuron activity
can support positive reinforcement. However, a subset of VTA neurons co-release DA and …

Ventral tegmental area glutamate neurons co-release GABA and promote positive reinforcement

JH Yoo, V Zell, N Gutierrez-Reed, J Wu… - Nature …, 2016 - nature.com
In addition to dopamine neurons, the ventral tegmental area (VTA) contains GABA-,
glutamate-and co-releasing neurons, and recent reports suggest a complex role for the …

Glutamate neurons within the midbrain dopamine regions

M Morales, DH Root - Neuroscience, 2014 - Elsevier
Midbrain dopamine systems play important roles in Parkinson's disease, schizophrenia,
addiction, and depression. The participation of midbrain dopamine systems in diverse …
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