A fundamental challenge in developmental biology is to understand how forces produced by
individual cells are patterned in space and time and then integrated to produce stereotyped …

Precise control of lineage segregation is critical for the development of multicellular
organisms, but our quantitative understanding of how variable signaling inputs are …

Ascidiella aspersa is an ascidian in the class of chordates—the closest relatives of
vertebrates. A. aspersa is a potential model organism for bio-imaging studies due to its …

During embryonic development, cell behaviors that are tightly coordinated both spatially and
temporally integrate at the tissue level and drive embryonic morphogenesis. Over the past …

Embryogenesis is a dynamic process with an intrinsic variability whose understanding
requires the integration of molecular, genetic, and cellular dynamics. Biological circuits …

During embryonic development, cell behaviors that are tightly coordinated both spatially and
temporally integrate at the tissue level and drive embryonic morphogenesis. Over the past …

Decades of studies on ascidian embryogenesis have culminated in deciphering the first
gene regulatory “blueprint” for the generation of all major larval tissue types in chordates …