Discovery of PANoptosis-related signatures correlates with immune cell infiltration in psoriasis

L Wu, X Jiao, M Jing, S Zhang, Y Wang, C Li, G Shi… - Plos one, 2024 - journals.plos.org
Psoriasis is an inflammatory skin disease that relapses frequently. Keratinocyte apoptosis
dysregulation plays a crucial role in the pathological mechanisms of psoriasis. PANoptosis …

Wogonin ameliorates the proliferation, inflammatory response, and pyroptosis in keratinocytes via NOD‐like receptor family pyrin domain containing 3/Caspase‐1 …

J Ma, C Ji, Y Sun, D Liu, K Pan… - … Inflammation and Disease, 2024 - Wiley Online Library
Background Psoriasis refers to a highly prevalent and immunologically mediated dermatosis
with considerable deterioration in life quality. Wogonin, a sort of flavonoid, has been …

Mesenchymal stem cell-derived exosomal microRNA-367-3p mitigates lower limb ischemia/reperfusion injury in mouse skeletal muscle via EZH2 targeting

H Sun, J Wang, W Bi, F Zhang, K Zhang… - Journal of Pharmacy …, 2024 - academic.oup.com
Objective This study aimed to investigate the protective effect of bone marrow mesenchymal
stem cell-derived exosomes (BMSCs-exo) against lower limb ischemia/reperfusion (I/R) …

Investigation and Confirmation of PYCARD as a Potential Biomarker for the Management of Psoriasis Disease

B Xu, B Yu, Z Xu, S Ye, Y Qing, H Sun… - Journal of …, 2024 - Taylor & Francis
Purpose Psoriasis is not yet completely curable, and its etiology and pathogenesis are
unclear. Necroptosis, also known as programmed necrosis, is a regulated mode of necrotic …

[HTML][HTML] Anti-inflammatory, immuno-modulatory, and anti-proliferative effects of 5-mer Oligogalacturonides (OG DP5) from citrus pectin on different types of human …

L Teyssier, L Olivier, B Estelle, C Marie-Jeanne… - Phytomedicine Plus, 2024 - Elsevier
Background Oligogalacturonides (OG) are natural plant cell wall pectin-derived products
with different degrees of polymerisation (DP) and methylation (M)(see Yu et al. 2022). Their …

[PDF][PDF] 银屑病的生物标志物

王傲雪 - 大连医科大学学报, 2023 - journal.dmu.edu.cn
银屑病是一种慢性, 复发性, 炎症性皮肤病. 近年来关于银屑病相关的生物标志物研究取得重要
进展. 本文综述了其主要的遗传, 组织和血清标志物, 包括预测疾病易感性, 监测疾病活动性 …

The roles of ubiquitination and deubiquitination of NLRP3 inflammasome in inflammation-related diseases: A review

S Tang, Y Geng, Y Wang, Q Lin, Y Yu, H Li - Biomolecules and …, 2024 - bjbms.org
The inflammatory response is a natural immune response that prevents microbial invasion
and repairs damaged tissues. However, excessive inflammatory responses can lead to …

Psoriasis-like inflammation induces mitochondrial function and structure changes in human keratinocytes and fibroblasts

G Kulkoviene, M Uldukyte, S Haluts, M Kairyte… - bioRxiv, 2024 - biorxiv.org
Mitochondrial structural and functional changes accompany psoriasis; however, the
mitochondrial response to psoriatic inflammation in keratinocytes and fibroblasts has not …

Life (and Death) in the Fas Lane: Novel Mediators of Fas Receptor Signaling

Z Magri - 2024 - search.proquest.com
Programmed cell death is a crucial regulatory mechanism of the immune system. Apoptosis,
pyroptosis, and necroptosis of leukocytes eliminate self-reactive, damaged, and infected …

Co-delivery of Tacrolimus and Thymoquinone topically by Nanostructured lipid carriers gel for enhanced efficacy against imiquimod-induced psoriasis in Balb/c mice

M Alam, M Rizwanullah, S Ahmad, A Iqubal, SR Mir… - 2024 - researchsquare.com
The primary objective of this current investigation is to evaluate the antipsoriatic potential of
a novel nanogel delivery system that co-encapsulates tacrolimus and thymoquinone within …