Collagens are the most abundant components of the extracellular matrix and many types of
soft tissues. Elastin is another major component of certain soft tissues, such as arterial walls …

Numerous epidemiological studies have consistently linked the presence of chronic
obstructive pulmonary disease (COPD) to the development of lung cancer, independently of …

The sites and patterns of tortuosity are dependent on key anatomic factors. These include:•
Anatomic fixation—vascular elongation between 2 fixed points will give rise to tortuosity. 16 …

Elastic fibres are insoluble components of the extracellular matrix of dynamic connective
tissues such as skin, arteries, lungs and ligaments. They are laid down during development …

Arterial dissections, which involve an abrupt tear in the wall of a major artery resulting in the
intramural accumulation of blood, are a family of catastrophic disorders causing major …

Collagens are the most abundant components of the extracellular matrix (ECM) and many
types of soft tissues. Elastin is another major component of certain soft tissues, such as …

A genetic influence on spontaneous pneumothoraces—those occurring without a traumatic
or iatrogenic cause—is supported by several lines of evidence: 1) pneumothorax can cluster …

Objectives: Review the diagnostic approaches and the importance of proper identification of
this condition. Describe the various differential diagnoses for Ehlers-Danlos syndrome …

Biogenesis of the mitochondrial oxidative phosphorylation system, which produces the bulk
of ATP for almost all eukaryotic cells, depends on the translation of 13 mtDNA-encoded …

The extracellular matrix (ECM) is a dynamic structure of molecules that can be divided into
six different categories and are collectively called the matrisome. The ECM plays pivotal …