Single agent checkpoint inhibitor therapy has not been effective for most gastrointestinal
solid tumors, but combination therapy with drugs targeting additional immunosuppressive …

The adenosine triphosphate (ATP)-binding cassette efflux transporter G2 (ABCG2) was
originally discovered in a multidrug-resistant breast cancer cell line. Studies in the past have …

Background Ferroptosis, which is characterized by lipid peroxidation and iron accumulation,
is closely associated with the pathogenesis of acute renal injury (AKI). Cyanidin-3-glucoside …

Background: Mitochondrial abnormalities play critical roles in diabetic tubular injury
progression. Dipeptidyl peptidase-4 (DPP4) inhibitors are widely used antihyperglycaemic …

Background: Chemokines are a family of proteins mainly mediating the homing and
migration of various cells. The CXC chemokine CXCL12 is a member of low-weight …

Kidney injury is a common complication of severe disease. Here, we report that injuries of
the zebrafish embryonal kidney are rapidly repaired by a migratory response in 2-, but not in …

Objective: We aimed to explore the protective effect of Panax notoginseng rhizomes (PNR)
on renal ischemia and reperfusion injury (RIRI) and the underlying molecular network …

Background: Stroke is the second leading cause of death worldwide. Angiogenesis
facilitates the formation of microvascular networks and promotes recovery after stroke. The …

Abstract Objective Application of Tandem Mass Tags (TMT)-based LC–MS/MS analysis to
screen for differentially expressed proteins (DEPs) in traumatic axonal injury (TAI) of the …

Purpose In this study, a series of in vitro experiments were performed to investigate the
molecular mechanisms underlying cell migration promoted by icariin (ICA) at low …