▪ Abstract Comparative modeling predicts the three-dimensional structure of a given protein
sequence (target) based primarily on its alignment to one or more proteins of known …

As a contribution to the celebration of the year 2014, declared by the United Nations to be
'The International Year of Crystallography', the FEBS Journal is dedicating this issue to …

Formation of the chromophore of green fluorescent protein (GFP) depends on the correct
folding of the protein. We constructed a" folding reporter" vector, in which a test protein is …

Obtaining an electron-density map from X-ray diffraction data can be difficult and time-
consuming even after the data have been collected, largely because MIR and MAD structure …

We developed and tested the I‐TASSER protein structure prediction algorithm in the CASP7
experiment, where targets are first threaded through the PDB library and continuous …

Structural genomics has the goal of obtaining useful, three-dimensional models of all
proteins by a combination of experimental structure determination and comparative model …

Motivation: The characterization of the folding degree of chains is central to the elucidation
of structure--function relationships in proteins. Here we present a new index for …

Tubby-like proteins (TULPs) are found in a broad range of multicellular organisms. In
mammals, genetic mutation of tubby or other TULPs can result in one or more of three …

The shapes of most protein sequences will be modeled based on their similarity to
experimentally determined protein structures. The current role, limitations, challenges and …

Structural genomics projects aim to provide an experimental or computational three-
dimensional model structure for all of the tractable macromolecules that are encoded by …