Glomerular podocytes are highly specialized cells with a complex cytoarchitecture. Their
most prominent features are interdigitated foot processes with filtration slits in between …

This review focuses on the intricate properties of the glomerular barrier. Other reviews have
focused on podocyte biology, mesangial cells, and the glomerular basement membrane …

Pathophysiology of proteinuria. Proteinuria is consequence of two mechanisms: the
abnormal transglomerular passage of proteins due to increased permeability of glomerular …

Albumin is filtered through the glomerulus with a sieving coefficient of 0.00062, which results
in approximately 3.3 g of albumin filtered daily in human kidneys. The proximal convoluted …

Recent progress in relating the functional properties of the glomerular capillary wall to its
unique structure is reviewed. The fenestrated endothelium, glomerular basement membrane …

Liposomes represent a widely varied and malleable class of drug carriers generally
characterized by the presence of one or more amphiphile bilayers enclosing an interior …

Biodegradable polymeric microneedles were developed as a method for achieving
sustained transdermal drug release. These microneedles have potential as a patient-friendly …

In this study, we pursued the somewhat controversial issue whether the glycosaminoglycans
(GAG) in the endothelial cell glycocalyx are important for glomerular size and charge …

Donepezil hydrochloride (DPH) is often used in the treatment of Alzheimer's disease. A new
treatment method was developed by encapsulating high DPH content in the tips of …

Biochemical and physiological processes that underlie the mechanism of albuminuria are
completely reassessed in this article in view of recent discoveries that filtered proteins …