Concerted nucleophilic aromatic substitution reactions
S Rohrbach, AJ Smith, JH Pang… - Angewandte Chemie …, 2019 - Wiley Online Library
Recent developments in experimental and computational chemistry have identified a rapidly
growing class of nucleophilic aromatic substitutions that proceed by concerted (cSNAr) …
growing class of nucleophilic aromatic substitutions that proceed by concerted (cSNAr) …
Benzothiazepines: Chemistry of a privileged scaffold
Benzothiazepines are one such class of heterocyclic scaffolds with celebrated biological
activities. The flooding of the pharmaceutical market with cardiovascular drugs like diltiazem …
activities. The flooding of the pharmaceutical market with cardiovascular drugs like diltiazem …
Dimethyl sulfoxide involved one-pot synthesis of quinoxaline derivatives
C Xie, Z Zhang, D Li, J Gong, X Han… - The Journal of organic …, 2017 - ACS Publications
An efficient, green, and novel method for the synthesis of N-heterocycle-fused quinoxalines
is reported herein. Dimethyl sulfoxide was used as both a reactant and a solvent in this …
is reported herein. Dimethyl sulfoxide was used as both a reactant and a solvent in this …
Transition-Metal-Free Synthesis of N-Arylphenothiazines through an N- and S-Arylation Sequence
An efficient synthetic method of N-arylphenothiazines from o-sulfanylanilines under
transition-metal-free conditions is disclosed. An N-and S-arylation sequence of o …
transition-metal-free conditions is disclosed. An N-and S-arylation sequence of o …
Metal-free β-amino alcohol synthesis: A two-step smiles rearrangement
D Yang, CX Xie, XT Wu, LR Fei, L Feng… - The Journal of Organic …, 2020 - ACS Publications
A novel method for the synthesis of β-amino alcohols has been demonstrated under mild
reaction conditions with a broad scope via a two-step Smiles rearrangement. What is more …
reaction conditions with a broad scope via a two-step Smiles rearrangement. What is more …
Fast construction of 1, 3-benzothiazepines by direct intramolecular dehydrogenative C–S bond formation of thioamides under metal-free conditions
WS Guo, H Gong, YA Zhang, LR Wen, M Li - Organic letters, 2018 - ACS Publications
The first general protocol for the synthesis of 1, 3-benzothiazepine derivatives was
established. With the aid of bench-stable hypervalent iodine promoter fluoro-HTIB, these …
established. With the aid of bench-stable hypervalent iodine promoter fluoro-HTIB, these …
Transition-metal-free synthesis of indole-fused dibenzo [b, f][1, 4] oxazepines via Smiles rearrangement
F Hu, H Liu, J Jia, C Ma - Organic & Biomolecular Chemistry, 2016 - pubs.rsc.org
A one-pot transition-metal-free approach for the synthesis of indole-fused dibenzo [b, f][1, 4]
oxazepines from 2-(1H-indol-2-yl) phenol and 1, 2-dihalobenzenes or 2 halonitroarenes has …
oxazepines from 2-(1H-indol-2-yl) phenol and 1, 2-dihalobenzenes or 2 halonitroarenes has …
Konzertierte nukleophile aromatische Substitutionen
S Rohrbach, AJ Smith, JH Pang, DL Poole… - Angewandte …, 2019 - Wiley Online Library
Jüngste Entwicklungen in der experimentellen und theoretischen Chemie haben zur
Identifizierung einer schnell wachsenden Klasse von nukleophilen aromatischen …
Identifizierung einer schnell wachsenden Klasse von nukleophilen aromatischen …
Annulations of Ynamides with 1, 2-Benzisothiazoles to Construct 1, 4-Benzothiazepines and 3-Aminoisoquinolines
XN Wang, Z Zhao, J Chen, N Wang, J Chang - Organic letters, 2024 - ACS Publications
Two distinct TMSOTf-catalyzed annulation reactions between ynamides and 1, 2-
benzisothiazoles have been developed. The direction of the reaction could be easily …
benzisothiazoles have been developed. The direction of the reaction could be easily …