Virus-related infectious diseases are serious threats to humans, which makes virus detection
of great importance. Traditional virus-detection methods usually suffer from low sensitivity …

DNA nanotechnology is a unique field, where physics, chemistry, biology, mathematics,
engineering, and materials science can elegantly converge. Since the original proposal of …

Conventional nucleic acid detection technologies usually rely on amplification to improve
sensitivity, which has drawbacks, such as amplification bias, complicated operation, high …

Engineering photo-plasmonic platforms with heterometallic nanohybrids are of paramount
significance for realizing augmented sensitivity in fluorescence-based analytical detection …

Our previously discovered monomeric aptamer for SARS-CoV-2 (MSA52) possesses a
universal affinity for COVID-19 spike protein variants but is ultimately limited by its ability to …

Surface proteins of cells are generally recognized through receptor–ligand interactions
(RLIs) in disease diagnosis, but their nonuniform spatial distribution and higher-order …

The immunological response of mast cells is controlled by the multivalent binding of
antigens to immunoglobulin E (IgE) antibodies bound to the high-affinity receptor FcεRI on …

Multivalent display of SARS-CoV-2 RBDs (receptor-binding domains, prime proteins for viral
infection and as vaccine immunogens) affects infectivity and as immunogens on a virus-like …

Lateral flow assay (LFA)-based rapid antigen tests are experiencing extensive global uptake
as an expeditious and highly effective modality for the screening of viral infections during the …

Virus-enveloping macromolecular shells or tilings can prevent viruses from entering cells.
Here, we describe the design and assembly of a cone-shaped DNA origami higher-order …