This thesis describes the isolation and structural elucidation of 17 new secondary
metabolites from Tongan marine sponges including examples of alkaloids, polyketides and …

Pateamine A (14) is a natural product that was extracted from a marine sponge off the coast
of the South Island of New Zealand. It exhibits potent biological activity, mediated by a …

Cyclopropanes and carbohydrates have long been used in the field of drug development.
Previous work has shown that 1, 2-cyclopropyl carbohydrates display bioactivity in both …