Progress in corneal wound healing
AV Ljubimov, M Saghizadeh - Progress in retinal and eye research, 2015 - Elsevier
Corneal wound healing is a complex process involving cell death, migration, proliferation,
differentiation, and extracellular matrix remodeling. Many similarities are observed in the …
differentiation, and extracellular matrix remodeling. Many similarities are observed in the …
Non-viral delivery systems for CRISPR/Cas9-based genome editing: Challenges and opportunities
L Li, S Hu, X Chen - Biomaterials, 2018 - Elsevier
In recent years, CRISPR (clustered regularly interspaced short palindromic repeat)/Cas
(CRISPR-associated) genome editing systems have become one of the most robust …
(CRISPR-associated) genome editing systems have become one of the most robust …
[HTML][HTML] Non viral vectors in gene therapy-an overview
M Ramamoorth, A Narvekar - Journal of clinical and diagnostic …, 2015 - ncbi.nlm.nih.gov
Non-viral vectors are simple in theory but complex in practice. Apart from intra cellular and
extracellular barriers, number of other challenges also needs to be overcome in order to …
extracellular barriers, number of other challenges also needs to be overcome in order to …
Lipid nanoparticle topology regulates endosomal escape and delivery of RNA to the cytoplasm
RNA therapeutics have the potential to resolve a myriad of genetic diseases. Lipid
nanoparticles (LNPs) are among the most successful RNA delivery systems. Expanding their …
nanoparticles (LNPs) are among the most successful RNA delivery systems. Expanding their …
Targeted delivery of CRISPR/Cas9‐mediated cancer gene therapy via liposome‐templated hydrogel nanoparticles
Due to its simplicity, versatility, and high efficiency, the clustered regularly interspaced short
palindromic repeat (CRISPR)/Cas9 technology has emerged as one of the most promising …
palindromic repeat (CRISPR)/Cas9 technology has emerged as one of the most promising …
Cationic liposomes as vectors for nucleic acid and hydrophobic drug therapeutics
Cationic liposomes (CLs) are effective carriers of a variety of therapeutics. Their applications
as vectors of nucleic acids (NAs), from long DNA and mRNA to short interfering RNA …
as vectors of nucleic acids (NAs), from long DNA and mRNA to short interfering RNA …
Self‐assembly of hyperbranched polymers and its biomedical applications
Hyperbranched polymers (HBPs) are highly branched macromolecules with a three‐
dimensional dendritic architecture. Due to their unique topological structure and interesting …
dimensional dendritic architecture. Due to their unique topological structure and interesting …
Drug delivery systems: Advanced technologies potentially applicable in personalized treatments
Advanced drug delivery systems (DDS) present indubitable benefits for drug administration.
Over the past three decades, new approaches have been suggested for the development of …
Over the past three decades, new approaches have been suggested for the development of …
Challenges in CRISPR/CAS9 delivery: potential roles of nonviral vectors
CRISPR/Cas9 genome editing platforms are widely applied as powerful tools in basic
research and potential therapeutics for genome regulation. The appropriate alternative of …
research and potential therapeutics for genome regulation. The appropriate alternative of …
Perspectives of using microRNA-loaded nanocarriers for epigenetic reprogramming of drug resistant colorectal cancers
OA Sukocheva, J Liu, ME Neganova… - Seminars in Cancer …, 2022 - Elsevier
Epigenetic regulation by microRNAs (miRs) demonstrated a promising therapeutic potential
of these molecules to regulate genetic activity in different cancers, including colorectal …
of these molecules to regulate genetic activity in different cancers, including colorectal …