MR Imaging of Human Brain Mechanics In Vivo: New Measurements to Facilitate the Development of Computational Models of Brain Injury

PV Bayly, A Alshareef, AK Knutsen, K Upadhyay… - Annals of biomedical …, 2021 - Springer
Computational models of the brain and its biomechanical response to skull accelerations
are important tools for understanding and predicting traumatic brain injuries (TBIs) …

Mechanical properties of the cranial meninges: a systematic review

DR Walsh, Z Zhou, X Li, J Kearns… - Journal of …, 2021 - liebertpub.com
The meninges are membranous tissues that are pivotal in maintaining homeostasis of the
central nervous system. Despite the importance of the cranial meninges in nervous system …

Validation and comparison of instrumented mouthguards for measuring head kinematics and assessing brain deformation in football impacts

Y Liu, AG Domel, SA Yousefsani, J Kondic… - Annals of Biomedical …, 2020 - Springer
Because of the rigid coupling between the upper dentition and the skull, instrumented
mouthguards have been shown to be a viable way of measuring head impact kinematics for …

Instantaneous whole-brain strain estimation in dynamic head impact

K Ghazi, S Wu, W Zhao, S Ji - Journal of Neurotrauma, 2021 - liebertpub.com
Head injury models are notoriously time consuming and resource demanding in simulations,
which prevents routine application. Here, we extend a convolutional neural network (CNN) …

In vivo estimates of axonal stretch and 3D brain deformation during mild head impact

AK Knutsen, AD Gomez, M Gangolli, WT Wang… - Brain multiphysics, 2020 - Elsevier
The rapid deformation of brain tissue in response to head impact can lead to traumatic brain
injury. In vivo measurements of brain deformation during non-injurious head impacts are …

Real-time dynamic simulation for highly accurate spatiotemporal brain deformation from impact

S Wu, W Zhao, S Ji - Computer methods in applied mechanics and …, 2022 - Elsevier
Real-time dynamic simulation remains a significant challenge for spatiotemporal data of
high dimension and resolution. In this study, we establish a transformer neural network …

Displacement-and strain-based discrimination of head injury models across a wide range of blunt conditions

W Zhao, S Ji - Annals of biomedical engineering, 2020 - Springer
Successful validation of a head injury model is critical to ensure its biofidelity. However,
there is an ongoing debate on what experimental data are suitable for model validation …

[HTML][HTML] A quantitative relationship between rotational head kinematics and brain tissue strain from a 2-D parametric finite element analysis

RW Carlsen, AL Fawzi, Y Wan, H Kesari, C Franck - Brain Multiphysics, 2021 - Elsevier
Given the complex nature of traumatic brain injury (TBI), assessment of injury risk directly
from kinematic measures of head motion remains a challenge. Despite this challenge …

Mechanical characterisation of the human dura mater, falx cerebri and superior sagittal sinus

DR Walsh, AM Ross, DT Newport, Z Zhou, J Kearns… - Acta biomaterialia, 2021 - Elsevier
The cranial meninges have been shown to play a pivotal role in traumatic brain injury
mechanopathology. However, while the mechanical response of the brain and its many …

Rheology of brain tissue and hydrogels: A novel hyperelastic and viscoelastic model for forensic applications

AL Yarin, V Kosmerl - Physics of Fluids, 2023 - pubs.aip.org
A new strain-energy function W, which possesses the strain energy expressible as a rational
function of the principal invariants of the Cauchy tensor C, is proposed. It generates a …