Prevalence of Plasmodium falciparum haplotypes associated with resistance to sulfadoxine–pyrimethamine and amodiaquine before and after upscaling of seasonal …

KB Beshir, J Muwanguzi, J Nader… - The Lancet Infectious …, 2023 - thelancet.com
Background Seasonal malaria chemoprevention is used in 13 countries in the Sahel region
of Africa to prevent malaria in children younger than 5 years. Resistance of Plasmodium …

Seasonal malaria chemoprevention in Africa and China's upgraded role as a contributor: a scoping review

M Xu, YX Hu, SN Lu, MA Idris, SD Zhou, J Yang… - Infectious Diseases of …, 2023 - Springer
Background Children under five are the vulnerable population most at risk of being infected
with Plasmodium parasites, especially in the Sahel region. Seasonal malaria …

[HTML][HTML] Mapping Antimalarial Drug Resistance in Mozambique: A Systematic Review of Plasmodium falciparum Genetic Markers Post-ACT Implementation

CRS Chaves, C da Silva, A Salamandane… - International Journal of …, 2024 - mdpi.com
Malaria continues to be a significant public health burden in many tropical and subtropical
regions. Mozambique ranks among the top countries affected by malaria, where it is a …

Whole-genome surveillance identifies markers of Plasmodium falciparum drug resistance and novel genomic regions under selection in Mozambique

E Coonahan, H Gage, D Chen, EV Noormahomed… - Mbio, 2023 - Am Soc Microbiol
The emergence of Plasmodium falciparum drug resistance threatens the efficacy of
antimalarial therapies globally. Population genomic studies have been instrumental in …

A snapshot of the prevalence of dihydropteroate synthase-431V mutation and other sulfadoxine-pyrimethamine resistance markers in Plasmodium falciparum isolates …

AJ Adegbola, OA Ijarotimi, AE Ubom, BA Adesoji… - Malaria Journal, 2023 - Springer
Background Malaria is a major public health issue with substantial risks among vulnerable
populations. Currently, the World Health Organization (WHO) recommends SP-IPTp in the …

Assessment of genetic polymorphisms associated with malaria antifolate resistance among the population of Libreville, Gabon

SD Dinzouna-Boutamba, BA Iroungou, FL Akombi… - Malaria Journal, 2023 - Springer
Background Gabon is a malaria-threatened country with a stable and hyperendemic
transmission of Plasmodium falciparum monoinfection. Malaria drug resistance is widely …

Prevalence of Mutations in the Pfdhfr, Pfdhps, and Pfmdr1 Genes of Malarial Parasites Isolated from Symptomatic Patients in Dogondoutchi, Niger

I Issa, MM Lamine, V Hubert, A Ilagouma… - Tropical Medicine and …, 2022 - mdpi.com
The effectiveness of artemisinin-based combination therapies (ACTs) depends not only on
that of artemisinin but also on that of partner molecules. This study aims to evaluate the …

The prevalence of molecular markers of resistance to sulfadoxine-pyrimethamine among pregnant women at first antenatal clinic attendance and delivery in the forest …

DK Dosoo, JA Bailey, KP Asante, FB Oppong, K Niaré… - Plos one, 2022 - journals.plos.org
Intermittent preventive treatment during pregnancy with sulfadoxine-pyrimethamine (IPTp-
SP) is used to prevent malaria and associated unfavorable maternal and foetal outcomes in …

Molecular epidemiology of drug resistance genes in plasmodium falciparum isolates imported from Nigeria between 2016 and 2020: continued emergence of fully …

X Wang, X Zhang, H Chen, J Zhang, Q Lu… - Microbiology …, 2022 - Am Soc Microbiol
Malaria poses public health threats worldwide. Nigeria accounted for the highest numbers of
cases (26.8%) and deaths (31.9%) among countries where malaria is endemic in 2020 …

Sub-microscopic Plasmodium falciparum infections and multiple drug resistant single nucleotide polymorphic alleles in pregnant women from southwestern Nigeria

AN Ibekpobaoku, MA Oboh, F Faal, E Adeniji… - BMC Research …, 2024 - Springer
Objectives The study evaluated sub-microscopic malaria infections in pregnancy using two
malaria Rapid Diagnostic Tests (mRDTs), microscopy and RT-PCR and characterized …