Nanostructure embedded microchips for detection, isolation, and characterization of circulating tumor cells

M Lin, JF Chen, YT Lu, Y Zhang, J Song… - Accounts of chemical …, 2014 - ACS Publications
Conspectus Circulating tumor cells (CTCs) are cancer cells that break away from either a
primary tumor or a metastatic site and circulate in the peripheral blood as the cellular origin …

Rational design of electrically conductive biomaterials toward excitable tissues regeneration

G Zhao, H Zhou, G Jin, B Jin, S Geng, Z Luo… - Progress in Polymer …, 2022 - Elsevier
Cells in vivo are situated in a complicated microenvironment composed of diverse
biochemical and biophysical cues. To regulate biological functions of cells, tissues and …

Bactericidal Effects of Natural Nanotopography of Dragonfly Wing on Escherichia coli

CD Bandara, S Singh, IO Afara, A Wolff… - … applied materials & …, 2017 - ACS Publications
Nanotextured surfaces (NTSs) are critical to organisms as self-adaptation and survival tools.
These NTSs have been actively mimicked in the process of developing bactericidal surfaces …

Nanostructured substrates for detection and characterization of circulating rare cells: from materials research to clinical applications

J Dong, JF Chen, M Smalley, M Zhao, Z Ke… - Advanced …, 2020 - Wiley Online Library
Circulating rare cells in the blood are of great significance for both materials research and
clinical applications. For example, circulating tumor cells (CTCs) have been demonstrated …

Engineering antifouling conducting polymers for modern biomedical applications

JG Wu, JH Chen, KT Liu, SC Luo - ACS applied materials & …, 2019 - ACS Publications
Conducting polymers are considered to be favorable electrode materials for implanted
biosensors and bioelectronics, because their mechanical properties are similar to those of …

Capturing cancer: emerging microfluidic technologies for the capture and characterization of circulating tumor cells

W Qian, Y Zhang, W Chen - Small, 2015 - Wiley Online Library
Circulating tumor cells (CTCs) escape from primary or metastatic lesions and enter into
circulation, carrying significant information of cancer progression and metastasis. Capture of …

NanoVelcro rare-cell assays for detection and characterization of circulating tumor cells

YJ Jan, JF Chen, Y Zhu, YT Lu, SH Chen… - Advanced drug delivery …, 2018 - Elsevier
Circulating tumor cells (CTCs) are cancer cells shredded from either a primary tumor or a
metastatic site and circulate in the blood as the potential cellular origin of metastasis. By …

Chitosan nanofibers for specific capture and nondestructive release of CTCs assisted by pCBMA brushes

N Sun, M Liu, J Wang, Z Wang, X Li, B Jiang, R Pei - Small, 2016 - Wiley Online Library
Over the last decade, significant progress has been made to develop sensitive devices for
the capture of circulating tumor cells (CTCs) from blood of cancer patients. However, simple …

PEDOT: PSS-based bioelectrodes for multifunctional drug release and electric cell-substrate impedance sensing

YS Hsiao, ED Quiñones, SC Yen, J Yu… - … Applied Materials & …, 2023 - ACS Publications
Electric cell-substrate impedance sensing (ECIS) is an innovative approach for the label-free
and real-time detection of cell morphology, growth, and apoptosis, thereby playing an …

Programming thermoresponsiveness of NanoVelcro substrates enables effective purification of circulating tumor cells in lung cancer patients

Z Ke, M Lin, JF Chen, J Choi, Y Zhang, A Fong… - ACS …, 2015 - ACS Publications
Unlike tumor biopsies that can be constrained by problems such as sampling bias,
circulating tumor cells (CTCs) are regarded as the “liquid biopsy” of the tumor, providing …