Recent advancements in stem cell technology open a new door for patients suffering from
diseases and disorders that have yet to be treated. Stem cell-based therapy, including …

Neutrophil elastase (NE) is a major inflammatory protease released by neutrophils and is
present in the airways of patients with cystic fibrosis (CF), chronic obstructive pulmonary …

Importance The benefits of surfactant administration via a thin catheter (minimally invasive
surfactant therapy [MIST]) in preterm infants with respiratory distress syndrome are …

During late lung development, alveolar and microvascular development is finalized to
enable sufficient gas exchange. Impaired late lung development manifests as …

Pulmonary surfactant is a critical component of lung function in healthy individuals. It
functions in part by lowering surface tension in the alveoli, thereby allowing for breathing …

Neutrophil elastase (NE), a major protease in the primary granules of neutrophils, is
involved in microbicidal activity. NE is an important factor promoting inflammation, has …

Bronchopulmonary dysplasia (BPD) is a major complication in prematurely born infants.
Pulmonary hypertension (PH) associated with BPD (BPD-PH) is characterized by alveolar …

Bronchopulmonary dysplasia (BPD) is the most common chronic lung disease in infants and
is associated with increased mortality, respiratory morbidity, neurodevelopmental …

Importance Bronchopulmonary dysplasia (BPD) is often associated with pulmonary vascular
disease and secondary pulmonary hypertension (PH). The pathogenesis of BPD-associated …

Bronchopulmonary dysplasia (BPD) is the most common respiratory disorder among infants
born extremely preterm. The pathogenesis of BPD involves multiple prenatal and postnatal …