Extracellular vesicles (EVs) are small bilipid layer-enclosed vesicles that can be secreted by
all tested types of brain cells. Being a key intercellular communicator, EVs have emerged as …

Cerebrospinal fluid (CSF) is a clear, transparent fluid derived from blood plasma that
protects the brain and spinal cord against mechanical shock, provides buoyancy, clears …

Amyotrophic lateral sclerosis (ALS) is described as a fatal and rapidly progressive
neurodegenerative disorder caused by the degeneration of upper motor neurons in the …

Neurodegenerative diseases such as amyotrophic lateral sclerosis (ALS) and Parkinson's
disease (PD) are both characterized by pathogenic protein aggregates that correlate with …

Small extracellular vesicles (EVs) are signalling messengers that regulate inter-tissue
communication through delivery of their molecular cargo. Here, we show that liver-derived …

Proteomics and metabolomics are two emerging fields that hold promise to shine light on the
molecular mechanisms causing neurodegenerative diseases. Research in this area may …

Extracellular vesicles (EVs) are particles released by multiple cells, encapsulated by lipid
bilayers and containing a variety of biological materials, including proteins, nucleic acids …

Amyotrophic lateral sclerosis (ALS) is a terminalneurodegenerative disease. Clinical and
molecular observations suggest that ALS pathology originates at a single site and spreads …

Objectives There is a lack of effective biomarkers for neurodegenerative diseases (NDs)
such as Alzheimer's disease (AD), Parkinson's disease (PD), amyotrophic lateral sclerosis …

Exosomes are a heterogeneous subset of extracellular vesicles (EVs) that biogenesis from
endosomes. Besides, exosomes contain a variety of molecular cargoes including proteins …