Recent applications of Kirkwood–Buff theory to biological systems

V Pierce, M Kang, M Aburi, S Weerasinghe… - Cell biochemistry and …, 2008 - Springer
The effect of cosolvents on biomolecular equilibria has traditionally been rationalized using
simple binding models. More recently, a renewed interest in the use of Kirkwood–Buff (KB) …

[HTML][HTML] Lipid-induced conformation and lipid-binding properties of cytolytic and antimicrobial peptides: determination and biological specificity

SE Blondelle, K Lohner, MI Aguilar - Biochimica et Biophysica Acta (BBA) …, 1999 - Elsevier
While antimicrobial and cytolytic peptides exert their effects on cells largely by interacting
with the lipid bilayers of their membranes, the influence of the cell membrane lipid …

Mechanism of helix induction by trifluoroethanol: a framework for extrapolating the helix-forming properties of peptides from trifluoroethanol/water mixtures back to …

P Luo, RL Baldwin - Biochemistry, 1997 - ACS Publications
To establish a framework for extrapolating the helix-forming properties of peptides from
TFE/H2O mixtures (TFE= 2, 2, 2-trifluoroethanol) back to water, the thermal unfolding curves …

Mechanism by which 2, 2, 2-trifluoroethanol/water mixtures stabilize secondary-structure formation in peptides: a molecular dynamics study

D Roccatano, G Colombo… - Proceedings of the …, 2002 - National Acad Sciences
Molecular dynamics simulation techniques have been used to investigate the effect of 2, 2, 2-
trifluoroethanol (TFE) as a cosolvent on the stability of three different secondary structure …

Clustering of fluorine-substituted alcohols as a factor responsible for their marked effects on proteins and peptides

DP Hong, M Hoshino, R Kuboi… - Journal of the American …, 1999 - ACS Publications
Among various alcohols, those substituted with fluorine, such as 2, 2, 2-trifluoroethanol
(TFE) or 3, 3, 3, 3 ', 3 ', 3 '-hexafluoro-2-propanol (HFIP), have a marked potential to induce …

Solvent effects in supramolecular chemistry: linear free energy relationships for common intermolecular interactions

F Würthner - The Journal of Organic Chemistry, 2021 - ACS Publications
The proper choice of solvent is of major importance for all studies in supramolecular
chemistry, including molecular recognition in host–guest systems, intramolecular folding …

Cooperative conformational transitions in phenylene ethynylene oligomers: Chain-length dependence

RB Prince, JG Saven, PG Wolynes… - Journal of the American …, 1999 - ACS Publications
Fluorescence quenching has been used to study the cooperative conformational transition
in a series of oligo (phenylene ethynylene) s having tri (ethylene glycol) monomethyl ether …

Structural determinants that target the hepatitis C virus core protein to lipid droplets

S Boulant, R Montserret, RG Hope, M Ratinier… - Journal of Biological …, 2006 - ASBMB
Hepatitis C virus core protein is targeted to lipid droplets, which serve as intracellular
storage organelles, by its C-terminal domain, termed D2. From circular dichroism and …

Cooperative α‐helix formation of β‐lactoglobulin and melittin induced by hexafluoroisopropanol

N Hirota, Y Goto, K Mizuno - Protein science, 1997 - Wiley Online Library
Alcohols denature the native state of proteins, and also stabilize the α‐helical conformation
in unfolded proteins and peptides. Among various alcohols, trifluoroethanol (TFE) and …

Helix propagation and N‐cap propensities of the amino acids measured in alanine‐based peptides in 40 volume percent trifluoroethanol

CA Rohl, A Chakrabartty, RL Baldwin - Protein Science, 1996 - Wiley Online Library
The helix propagation and N‐cap propensities of the amino acids have been measured in
alanine‐based peptides in 40 volume percent trifluoroethanol (40% TFE) to determine if this …