Geographical Distribution of MTHFR C677T, A1298C and MTRR A66G Gene Polymorphisms in China: Findings from 15357 Adults of Han Nationality

B Yang, Y Liu, Y Li, S Fan, X Zhi, X Lu, D Wang… - PloS one, 2013 - journals.plos.org
Background Methylenetetrahydrofolate reductase (MTHFR) C677T, A1298C and methionine
synthase reductase (MTRR) A66G polymorphisms are important genetic determinants for …

Primer1: primer design web service for tetra-primer ARMS-PCR

A Collins, X Ke - The Open Bioinformatics Journal, 2012 - benthamopen.com
Tetra-primer ARMS-PCR is used extensively as a low cost, single PCR assay requiring no
post-PCR manipulation. The design of successful primers depends on a number of variables …

Association between MTHFR C677T and A1298C, and MTRR A66G polymorphisms and susceptibility to schizophrenia in a Syrian study cohort

B Lajin, AA Sakur, R Michati, A Alachkar - Asian journal of psychiatry, 2012 - Elsevier
The folate–homocystiene metabolic pathway has been shown to be involved in the
susceptibility for developing schizophrenia by several studies. In the present study we …

A fully integrated nucleic acid analysis system for multiplex detection of genetic polymorphisms related to folic acid metabolism

B Lin, Z Geng, Y Chen, W Zeng, B Li, Y Zhang, P Liu - Lab on a Chip, 2023 - pubs.rsc.org
A sufficient intake of folic acid is essential during pregnancy, but several genetic
polymorphisms reduce its absorption, threaten the lives of pregnant women and cause …

[HTML][HTML] Association of two methylenetetrahydrofolate reductase polymorphisms (rs1801133, rs1801131) with the risk of type 2 diabetes in South-East of Iran

M Poodineh, R Saravani, M Mirhosseini… - … of biochemistry & …, 2019 - ncbi.nlm.nih.gov
Background: DNA methylation has been linked to the development and progression of
multiple disorders including T2D. One significant enzyme involved in DNA methylation is …

Investigation of sensitivity, specificity and accuracy of Tetra primer ARMS PCR method in comparison with conventional ARMS PCR, based on sequencing technique …

MA Honardoost, H Tabatabaeian, M Akbari, M Salehi - Gene, 2014 - Elsevier
Purpose Beta thalassemia is one of the most important hematic diseases all around the
world and solving the problems caused by this abnormality is strongly dependent on precise …

Association of polymorphisms in one-carbon metabolizing genes with breast cancer risk in Syrian women

B Lajin, A Alhaj Sakur, L Ghabreau, A Alachkar - Tumor Biology, 2012 - Springer
Dietary folate status as well as polymorphisms in one-carbon metabolism genes may affect
the risk of breast cancer through aberrant DNA methylation and altered nucleotide synthesis …

SYBR green dye-based probe-free SNP genotyping: Introduction of T-Plex real-time PCR assay

I Baris, O Etlik, V Koksal, Z Ocak, ST Baris - Analytical Biochemistry, 2013 - Elsevier
Single-nucleotide polymorphism (SNP) genotyping is widely used in genetic association
studies to characterize genetic factors underlying inherited traits. Despite many recent …

Association between Methylenetetrahydrofolate Reductase (MTHFR) and 5-Methyltetrahydrofolate-Homocysteine Methyltransferase Reductase (MTRR) …

SF Alsaffar, NN Baqer - Iranian Journal of Medical Sciences, 2024 - pmc.ncbi.nlm.nih.gov
Background: The methylenetetrahydrofolate reductase (MTHFR) gene is an essential gene
in the metabolism of folate-homocysteine. Recently, the level of homocysteine was found to …

[HTML][HTML] Genetic variants and breast carcinoma susceptibility: Unveiling the role of MTHFR (rs1801131, rs1801133) and TP53 (rs1042522)

WE Nouh, EF El Azab, EA Oraby, SM Ahmed… - Gene, 2025 - Elsevier
Background The contribution of MTHFR and TP53 genetic variants to breast carcinoma (BC)
susceptibility has been examined, but their findings have been inconclusive. This work is …