ImmunoPET: concept, design, and applications

W Wei, ZT Rosenkrans, J Liu, G Huang, QY Luo… - Chemical …, 2020 - ACS Publications
Immuno-positron emission tomography (immunoPET) is a paradigm-shifting molecular
imaging modality combining the superior targeting specificity of monoclonal antibody (mAb) …

Radiolabeled peptides and antibodies in medicine

P Kręcisz, K Czarnecka, L Królicki… - Bioconjugate …, 2020 - ACS Publications
Radiolabeled peptides are a relatively new, very specific radiotracer group, which is still
expanding. This group is very diverse in terms of peptide size. It contains very small …

Modulation of cellular function by the urokinase receptor signalling: A mechanistic view

D Alfano, P Franco, MP Stoppelli - Frontiers in Cell and …, 2022 - frontiersin.org
Urokinase-type plasminogen activator receptor (uPAR or CD87) is a glycosyl-phosphatidyl-
inositol anchored (GPI) membrane protein. The uPAR primary ligand is the serine protease …

[HTML][HTML] Personalized targeted therapeutic strategies against oral squamous cell carcinoma. An evidence-based review of literature

M Cao, E Shi, H Wang, L Mao, Q Wu, X Li… - International Journal …, 2022 - ncbi.nlm.nih.gov
Oral squamous cell carcinoma (OSCC) is the most common type of malignant tumor in the
head and neck, with a poor prognosis mainly due to recurrence and metastasis. Classical …

Therapeutic strategies targeting urokinase and its receptor in cancer

MT Masucci, M Minopoli, G Di Carluccio, ML Motti… - Cancers, 2022 - mdpi.com
Simple Summary The uPA/uPAR system is highly involved in cancer progression and
metastasis. Many studies have definitively assessed that the high expression of urokinase …

[HTML][HTML] uPAR: an essential factor for tumor development

T Lv, Y Zhao, X Jiang, H Yuan, H Wang, X Cui… - Journal of …, 2021 - ncbi.nlm.nih.gov
Tumorigenesis is closely related to the loss of control of many genes. Urokinase-type
plasminogen activator receptor (uPAR), a glycolipid-anchored protein on the cell surface, is …

A comparative study of clinical intervention and interventional photothermal therapy for pancreatic cancer

Y Hu, C Chi, S Wang, L Wang, P Liang, F Liu… - Advanced …, 2017 - Wiley Online Library
Although nanoparticle‐based photothermal therapy (PTT) has been intensively investigated
recently, its comparative efficiency with any clinical cancer treatments has been rarely …

Molecular targeted NIR-II probe for image-guided brain tumor surgery

S Kurbegovic, K Juhl, H Chen, C Qu, B Ding… - Bioconjugate …, 2018 - ACS Publications
Optical imaging strategies for improving delineation of glioblastoma (GBM) is highly desired
for guiding surgeons to distinguish cancerous tissue from healthy and precious brain tissue …

Recent development of small-molecule organic fluorophores for multifunctional bioimaging in the second near-infrared window

Q Shen, S Wang, ND Yang, C Zhang, Q Wu… - Journal of …, 2020 - Elsevier
The optical wavelength between 1000 and 1700 nm, commonly referred to as the second
near-infrared (NIR-II) window, has become a highly popular optical region for multifunctional …

Recent nanotheranostic approaches in cancer research

D Gupta, P Roy, R Sharma, R Kasana… - Clinical and …, 2024 - Springer
Humanity is suffering from cancer which has become a root cause of untimely deaths of
individuals around the globe in the recent past. Nanotheranostics integrates therapeutics …