Targeting cancer stem cells by dietary agents: an important therapeutic strategy against human malignancies

M Deldar Abad Paskeh, S Asadi, A Zabolian… - International Journal of …, 2021 - mdpi.com
As a multifactorial disease, treatment of cancer depends on understanding unique
mechanisms involved in its progression. The cancer stem cells (CSCs) are responsible for …

Phenolic acids-mediated regulation of molecular targets in Ovarian Cancer: current understanding and future perspectives

N Nazam, NR Jabir, I Ahmad, SA Alharthy, MS Khan… - Pharmaceuticals, 2023 - mdpi.com
Cancer is a global health concern with a dynamic rise in occurrence and one of the leading
causes of mortality worldwide. Among different types of cancer, ovarian cancer (OC) is the …

Polyphenol-mediated autophagy in cancer: evidence of in vitro and in vivo studies

M Benvenuto, L Albonici, C Focaccetti, S Ciuffa… - International Journal of …, 2020 - mdpi.com
One of the hallmarks of cellular transformation is the altered mechanism of cell death. There
are three main types of cell death, characterized by different morphological and biochemical …

Mechanism and regulation of mitophagy in nonalcoholic fatty liver disease (NAFLD): A mini-review

L Zhu, X Wu, R Liao - Life Sciences, 2023 - Elsevier
Mitochondrial dysfunction has been hypothesized to play a central role in the pathobiology
of nonalcoholic fatty liver disease (NAFLD). Thus, maintenance of mitochondria homeostasis …

Quantitative conversion of free, acid-hydrolyzable, and bound ellagic acid in walnut kernels during baking

X Guo, F Gu, T Yang, Z Shao, Q Zhang, J Zhu, F Wang - Food Chemistry, 2023 - Elsevier
Ellagitannins, the main components of walnut kernel polyphenols, are easily degraded by
heating to produce ellagic acid, precursor in the production of urolithins that show multiple …

Role of autophagy and its regulation by noncoding RNAs in ovarian cancer

C Feng, X Yuan - Experimental Biology and Medicine, 2023 - journals.sagepub.com
Autophagy is a self-digestion process by which misfolded proteins and damaged organelles
in eukaryotic cells are degraded to maintain cellular homeostasis. This process is involved …

[HTML][HTML] In vitro assessment of dietary bioactives for TFEB activation as a possible target to support cognitive and emotional wellbeing

L Trovò, A Vaucher, Y Pan, P Steiner, S Flunkert… - Journal of Functional …, 2023 - Elsevier
Aging and chronic stress are associated with altered brain plasticity and an increased risk of
developing cognitive and emotional health problems. A key cellular mechanism involved is …

The crosstalk between Toll and AMPK signaling pathways mediates growth inhibition of Eriocheir sinensis under deltamethrin stress

Q Ren, X Nie, X Ma, Z Han, Y Li, X Yang, L Ji, R Su… - Aquatic Toxicology, 2024 - Elsevier
Hepatopancreatic necrosis disease (HPND) broke out in 2015 in the Eriocheir sinensis
aquaculture region of Xinghua, Jiangsu Province; however, the specific cause of HPND …

Ellagic acid-a dietary polyphenol with anticancer activity that deserves more consideration

M Djaldetti - Recent Progress in Nutrition, 2023 - lidsen.com
Ellagic acid (EA) the principal polyphenol of pomegranate (Punicca granatum) is renowned
for its beneficial therapeutic activity in several diseases including cancer. Studies have …

Advances in natural products modulating autophagy influenced by cellular stress conditions and their anticancer roles in the treatment of ovarian cancer

D Li, D Geng, M Wang - The FASEB Journal, 2024 - Wiley Online Library
Autophagy is a conservative catabolic process that typically serves a cell‐protective function.
Under stress conditions, when the cellular environment becomes unstable, autophagy is …