GLP-1 receptor agonists in non-alcoholic fatty liver disease: current evidence and future perspectives

R Nevola, R Epifani, S Imbriani, G Tortorella… - International Journal of …, 2023 - mdpi.com
To date, non-alcoholic fatty liver disease (NAFLD) is the most frequent liver disease,
affecting up to 70% of patients with diabetes. Currently, there are no specific drugs available …

Nonalcoholic fatty liver disease in adults: current concepts in etiology, outcomes, and management

T Marjot, A Moolla, JF Cobbold, L Hodson… - Endocrine …, 2020 - academic.oup.com
Nonalcoholic fatty liver disease (NAFLD) is a spectrum of disease, extending from simple
steatosis to inflammation and fibrosis with a significant risk for the development of cirrhosis. It …

Hepatic insulin receptor: new views on the mechanisms of liver disease

WH Lee, SM Najjar, CR Kahn, TD Hinds Jr - Metabolism, 2023 - Elsevier
Over 65% of people with obesity display the metabolic-associated fatty liver disease
(MAFLD), which can manifest as steatohepatitis, fibrosis, cirrhosis, or liver cancer. The …

Effects of newer antidiabetic drugs on nonalcoholic fatty liver and steatohepatitis: Think out of the box!

G Ranjbar, DP Mikhailidis, A Sahebkar - Metabolism, 2019 - Elsevier
Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disease in
Western societies and a major cause of hepatic disease worldwide. Its more severe type …

Efficacy and safety of GLP-1 receptor agonists in patients with type 2 diabetes mellitus and non-alcoholic fatty liver disease: a systematic review and meta-analysis

Y Zhu, J Xu, D Zhang, X Mu, Y Shi, S Chen… - Frontiers In …, 2021 - frontiersin.org
The prevalence of non-alcoholic fatty liver disease (NAFLD) in patients with type 2 diabetes
mellitus (T2DM) is increasing and there is an urgent need for new treatment strategy to …

Gut-pancreas-liver axis as a target for treatment of NAFLD/NASH

G Svegliati-Baroni, B Patrício, G Lioci… - International journal of …, 2020 - mdpi.com
Non-alcoholic fatty liver disease (NAFLD) represents the most common form of chronic liver
disease worldwide. Due to its association with obesity and diabetes and the fall in hepatitis …

Future perspectives on GLP-1 receptor agonists and GLP-1/glucagon receptor co-agonists in the treatment of NAFLD

M Seghieri, AS Christensen, A Andersen… - Frontiers in …, 2018 - frontiersin.org
Along the obesity pandemic, the prevalence of non-alcoholic fatty liver disease (NAFLD),
often regarded as the hepatic manifestation of the metabolic syndrome, increases worldwide …

[HTML][HTML] Beneficial effect of anti-diabetic drugs for nonalcoholic fatty liver disease

KS Kim, BW Lee - Clinical and molecular hepatology, 2020 - ncbi.nlm.nih.gov
Nonalcoholic fatty liver disease (NAFLD) is the most common liver disorder and is
associated with various metabolic diseases, including type 2 diabetes mellitus. There are no …

Glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) for the management of nonalcoholic fatty liver disease (NAFLD): a systematic review

X Lv, Y Dong, L Hu, F Lu, C Zhou… - … , diabetes & metabolism, 2020 - Wiley Online Library
There are no licensed drugs for nonalcoholic fatty liver disease (NAFLD), and there is a lack
of consensus on the best outcome measures for controlled trials. This systematic review …

[HTML][HTML] Glucagon-like peptide-1 receptor agonists in non-alcoholic fatty liver disease: An update

A Sofogianni, A Filippidis, L Chrysavgis… - World Journal of …, 2020 - ncbi.nlm.nih.gov
Non-alcoholic fatty liver disease (NAFLD) is the predominant cause of chronic liver disease
worldwide. NAFLD progresses in some cases to non-alcoholic steatohepatitis (NASH) …