Electrophoresis of DNA and other polyelectrolytes: Physical mechanisms

JL Viovy - Reviews of Modern Physics, 2000 - APS
The dramatic recent advances in molecular biology, which have opened a new era in
medicine and biotechnology, rely on improved techniques to study large molecules …

Principles of DNA separation with capillary electrophoresis

C Heller - Electrophoresis, 2001 - Wiley Online Library
During the last decade, capillary electrophoresis (CE) of DNA has undergone rapid
development. This improvement was especially important for DNA sequencing, where CE …

Modeling the separation of macromolecules: A review of current computer simulation methods

GW Slater, C Holm, MV Chubynsky… - …, 2009 - Wiley Online Library
Abstract Theory and numerical simulations play a major role in the development of improved
and novel separation methods. In some cases, computer simulations predict counterintuitive …

Effect of the matrix on DNA electrophoretic mobility

NC Stellwagen, E Stellwagen - Journal of Chromatography A, 2009 - Elsevier
DNA electrophoretic mobilities are highly dependent on the nature of the matrix in which the
separation takes place. This review describes the effect of the matrix on DNA separations in …

Nanospheres for DNA separation chips

M Tabuchi, M Ueda, N Kaji, Y Yamasaki… - Nature …, 2004 - nature.com
We report here a technology to carry out separations of a wide range of DNA fragments with
high speed and high resolution. The approach uses a nanoparticle medium, core-shell type …

Separation of long double-stranded DNA by nanoparticle-filled capillary electrophoresis

MF Huang, YC Kuo, CC Huang, HT Chang - Analytical chemistry, 2004 - ACS Publications
We present the first example of the analysis of long double-stranded (ds) DNA molecules by
nanoparticle-filled capillary electrophoresis (NFCE). To avoid aggregation of the gold …

[HTML][HTML] Ions' motion in water

P Banerjee, B Bagchi - The Journal of chemical physics, 2019 - pubs.aip.org
Over the decades, a great deal of attention has been focused on the solvation and transport
properties of small rigid monatomic ions such as Na+, K+, Li+, Cl−, and Br− due to their …

Polymeric matrices for DNA sequencing by capillary electrophoresis

MN Albarghouthi, AE Barron - … : An International Journal, 2000 - Wiley Online Library
We review the wide range of polymeric materials that have been employed for DNA
sequencing separations by capillary electrophoresis. Intensive research in the area has …

Theory of DNA electrophoresis: A look at some current challenges

GW Slater, C Desruisseaux, SJ Hubert… - …, 2000 - Wiley Online Library
Although electrophoresis is one of the basic methods of the modern molecular biology
laboratory, new ideas are being suggested at an accelerated rate, in large part because of …

The effects of polymer properties on DNA separations by capillary electrophoresis in uncross‐linked polymer solutions

AE Barron, WM Sunada, HW Blanch - Electrophoresis, 1996 - Wiley Online Library
Low‐viscosity, aqueous solutions of hydrophilic linear polymers have been shown to be
useful for the separation of DNA restriction fragments by capillary electrophoresis (CE) …