Survivin (also known as BIRC5) is an evolutionarily conserved eukaryotic protein that is
essential for cell division and can inhibit cell death. Normally it is only expressed in actively …

Survivin, a member of the inhibitor of apoptosis (IAP) protein family that inhibits caspases
and blocks cell death, is highly expressed in most cancers and is associated with a poor …

Survivin is a member of the family of inhibitors of apoptosis proteins (IAPs). It is involved in
the normal mitotic process and acts as an anti-apoptotic molecule. While terminally …

Various studies have shown that the cell-cycle-related regulatory proteins UBE2C, PLK1,
and BIRC5 promote cell proliferation and migration in different types of cancer. However …

Survivin is a member of the inhibitor of apoptosis (IAP) family and has multifunctional
properties that include aspects of proliferation, invasion and cell survival control. Survivin is …

Alternative pre-mRNA splicing allows exons of pre-mRNA to be spliced in different
arrangements to produce functionally distinct mRNAs. More than 95% of human genes …

Significance: Several therapeutic strategies for cancer treatments have been developed with
time, and significant milestones have been achieved recently. However, with these novel …

Background The survivin polymorphisms have been shown to confer genetic susceptibility to
various tumors, but the results are inconsistent. In order to accomplish a more precise …

To investigate the association of survivin− 31G/C,− 141G/C, and− 241T/C polymorphisms
with colorectal cancer (CRC) susceptibility and explore the mechanisms of the survivin …

Purpose: To investigate the expressions of caspase-3 and survivin in colorectal cancer
patients and their possible associations with clinicopathological parameters and the …